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The Role of Glucocorticoid-induced Tumour Necrosis Factor Receptor (GITR) Co-Stimulation in Establishing Early Viral Control during Chronic Viral Infection

The Role of Glucocorticoid-induced Tumour Necrosis Factor Receptor (GITR) Co-Stimulation in Establishing Early Viral Control during Chronic Viral Infection
糖皮质激素诱导的肿瘤坏死因子受体 (GITR) 共刺激在慢性病毒感染期间建立早期病毒控制中的作用
批准号：
331231
负责人：
Chang Yu-Han
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-12-01 至 2015-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331231&lang=en
关键词：
Antigen Presenting Cells (Apc) Subsets Cd4 T Helper Cell Cd8 Cytotoxic T Cell Chronic Lymphocytic Choriomeningitis Virus (Lcmv) Chronic Viral Infection Gitr-Dependent T Cell Co-Stimulation Glucocorticoid-Induced Tnf Receptor (Gitr) Glucocorticoid-I

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Despite advances in antiviral therapy, chronic viral infections remain a major burden on global health. Normally upon viral infection, our immune system up-regulates an array of molecules on white blood cells to stimulate immune responses required for vir
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