Genetic control of epigenomic landscapes by the ISWI protein family during differentiation

ISWI 蛋白家族在分化过程中对表观基因组景观的遗传控制

• 批准号: 321436
• 负责人: Picketts David J
• 金额: $ 65.45万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-03-01 至 2020-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=321436&lang=en
• 关键词: Chip-Seq; Chromatin Remodeling; Differentiation; Engrailed; Epigenetics; Foxg1; Iswi; Transcription

All of our genes are arranged on large pieces of DNA called chromosomes. The chromosomes are huge molecules that must undergo multiple levels of compaction to fit into the cell. At the same time, the genes characteristic of that cell type must remain acce

我们所有的基因都排列在称为染色体的大块DNA上。染色体是巨大的分子，必须经历多层次的压缩才能适应细胞。与此同时，这种细胞类型的基因特征必须保持接入，