Topical Granzyme B Inhibitors for Wound Healing and Scarring
Topical Granzyme B Inhibitors for Wound Healing and Scarring
批准号:
324707
负责人:
Granville David J
金额:
$17.27万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-03-01 至 2018-03-01
中文摘要
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英文摘要
Granzyme B (GzmB) is a protein-degrading enzyme that is induced by sunlight (UV). When GzmB is elevated in the skin, it prevents the skin from repairing itself and this can lead to scarring. Our previous work, in which we genetically knocked out GzmB, sho
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