Development and validation of synthetic bone and soft tissue analogues for surgical training (Phase I)

用于外科训练的合成骨和软组织类似物的开发和验证（第一阶段）

• 批准号: 476890-2015
• 负责人: Anglin, Carolyn
• 金额: $ 9.11万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=578767
• 关键词: Development; validation; synthetic; bone; soft

Our team has developed a synthetic bone analogue that mimics the tactile feel of bone when using orthopaedic instruments. Residents can use this training system to learn and practice key orthopaedic skills. To date, surgical training has usually occurred on patients in a master-apprentice model. However, physical and virtual simulators are increasingly seen as essential to a resident's education, to improve patient safety and for more efficient learning. To be effective, they must realistically represent the key features and must be validated. In addition to feeling more like bone than existing models, our models represent a harder outer cortical layer, softer, inner cancellous bone, and a transition between the two. The material properties can be tuned such that they represent weak (osteoporotic), normal or strong bone, and can be shaped in normal or abnormal geometry, and can be seen realistically in an X-ray. Three applications include: pedicle screw placement training for spinal surgery, knee replacement surgery training, and biomechanical testing of implants and instruments. Collaborating with our technology transfer office, Innovate Calgary, our team consists of engineers, a spinal surgeon/entrepreneur, business professor/entrepreneur, biochemist, veterinary anaesthesiologist/educator and artist. End users interested in using the bone models include orthopaedic companies, academic training centres and researchers. The purpose of the proposed research is to: improve the models based on user feedback; create new bone models; reduce manufacturing costs further (they are already inexpensive, but could be even more so with automation); add realistic soft tissues; create validated teaching modules; validate the models mechanically and with orthopaedic residents; and test business assumptions. Our goal is to use the results of this research to create a spin-off company, benefiting Canada and improving patient safety.

我们的团队开发了一种合成骨类似物，可以模仿使用骨科器械时骨骼的触觉。住院医师可以使用这个培训系统来学习和练习关键的骨科技能。迄今为止，外科手术培训通常以师徒模式对患者进行。然而，物理和虚拟模拟器越来越被视为对住院医师教育、提高患者安全和提高学习效率至关重要。为了有效，它们必须真实地代表关键特征并且必须经过验证。 除了比现有模型感觉更像骨骼之外，我们的模型还代表了较硬的外皮质层、较软的内部松质骨以及两者之间的过渡。可以调整材料特性，使其代表弱（骨质疏松）、正常或强健的骨骼，并且可以形成正常或异常的几何形状，并且可以在 X 射线中真实地看到。三种应用包括：脊柱手术的椎弓根螺钉置入训练、膝关节置换手术训练以及植入物和器械的生物力学测试。 我们的团队与我们的技术转让办公室“创新卡尔加里”合作，由工程师、脊柱外科医生/企业家、商业教授/企业家、生物化学家、兽医麻醉师/教育家和艺术家组成。对使用骨骼模型感兴趣的最终用户包括骨科公司、学术培训中心和研究人员。 本研究的目的是：根据用户反馈改进模型；创建新的骨骼模型；进一步降低制造成本（它们已经很便宜，但如果采用自动化，可能会更便宜）；添加真实的软组织；创建经过验证的教学模块；与骨科医生一起机械地验证模型；并测试业务假设。我们的目标是利用这项研究的结果创建一家分拆公司，使加拿大受益并提高患者的安全。