Thoracic stents design
Thoracic stents design
批准号:
483299-2015
负责人:
Grecov, Dana
金额:
$1.82万
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31
中文摘要
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英文摘要
As analyzed by World Health Organization (WHO), cardiovascular diseases were the leading cause of death in
2012. Among various cardiovascular diseases, acute aortic dissection is the most common and life-threatening
emergency that requires immediate attention. While traditional open surgical procedures remain the gold
standard for treating aortic dissection, approximately 30% of the patients are unfit for surgical procedures due
to various reasons. Type A aortic dissection occurs in roughly 62% of patients and has a high mortality rate of
26% (with surgery) and 56% (with medical treatment and without surgery); therefore, one potential alternative
for treating aortic dissection is the endovascular aortic repair (EVAR) using thoracic stents.
The main objective of this project is to numerically investigate the hemodynamics of existing available stent
graft models with the focus on geometrical variance around ascending aorta. The investigation of the potential
device design for thoracic aorta will be carried out by computational methods, which will be used as a rapid
prototype design tool. In addition, patient-specific models will be studied to gain further insight on the
hemodynamic variance under complex topography.
A first-time collaboration will be established between Dr. Dana Grecov from the University of British
Columbia and Agile MV to study and design new improved thoracic stents.
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