Thoracic stents design

根据世界卫生组织(世卫组织)的分析，心血管疾病是#年的主要死亡原因。 2012年。在各种心血管疾病中，急性主动脉夹层是最常见和危及生命的疾病。 需要立即注意的紧急情况。虽然传统的开放外科手术仍然是黄金 作为治疗主动脉夹层的标准，大约30%的患者因 原因多种多样。A型主动脉夹层发生在大约62%的患者中，死亡率高达 26%(接受手术)和56%(接受治疗和不接受手术)；因此，一个潜在的替代方案 治疗主动脉夹层的方法是使用胸腔内支架行主动脉腔内修复术(EVAR)。 该项目的主要目标是数值研究现有支架的血流动力学。 关注升主动脉周围几何变异的移植物模型。对潜力的调查 胸主动脉装置的设计将通过计算方法进行，这将作为一种快速的 原型设计工具。此外，还将研究特定于患者的模型，以进一步了解 复杂地形下血流动力学变化。 英国大学的达纳·格列科夫博士将首次合作 哥伦比亚大学和雅居乐MV合作研究和设计新的改进型胸腔支架。

As analyzed by World Health Organization (WHO), cardiovascular diseases were the leading cause of death in 2012. Among various cardiovascular diseases, acute aortic dissection is the most common and life-threatening emergency that requires immediate attention. While traditional open surgical procedures remain the gold standard for treating aortic dissection, approximately 30% of the patients are unfit for surgical procedures due to various reasons. Type A aortic dissection occurs in roughly 62% of patients and has a high mortality rate of 26% (with surgery) and 56% (with medical treatment and without surgery); therefore, one potential alternative for treating aortic dissection is the endovascular aortic repair (EVAR) using thoracic stents. The main objective of this project is to numerically investigate the hemodynamics of existing available stent graft models with the focus on geometrical variance around ascending aorta. The investigation of the potential device design for thoracic aorta will be carried out by computational methods, which will be used as a rapid prototype design tool. In addition, patient-specific models will be studied to gain further insight on the hemodynamic variance under complex topography. A first-time collaboration will be established between Dr. Dana Grecov from the University of British Columbia and Agile MV to study and design new improved thoracic stents.