Hemodynamics of device treated sidewall cerebral aneurysms**
Hemodynamics of device treated sidewall cerebral aneurysms**
批准号:
534003-2018
负责人:
Grecov, Dana
金额:
$1.82万
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-01-01 至 2019-12-31
中文摘要
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英文摘要
Cerebral aneurysms are cerebrovascular abnormality characterized by the weakening and dilation of a localized area of the wall of a cerebral artery. The reasons for aneurysm initiation, growth, and rupture are complicated and not well understood. Generally, it is recognized that hemodynamics play a key role in these processes given that the flow behavior is dependent on the geometrical characteristics of the flow domain. Stents are often deployed to treat cerebral aneurysms on where flow alterations occur within the aneurysm sac following the stent deployment.**Evasc is a medical device company focusing on developing leading edge solutions for treating cerebral aneurysms. Within Evasc's product portfolio, there is a need to further refine existing stent for treating sidewall aneurysms. Given that the current modular experimental setup has been developed at the Industrial and Biological Multiphysics Laboratory at UBC and can easily be adapted to be used for the investigation of sidewall cerebral aneurysms, a thorough investigation will be conducted to determine the effects of their anatomical characteristics on the effectiveness of different stents. **The main objective of this project is to investigate the effectiveness of existing endovascular stents, provided by Evasc, under the various anatomical configurations of sidewall cerebral aneurysms using our in-house developed modular cardiovascular flow simulator as well as Computational Fluid Dynamics (CFD) studies. Based on the results from this project, Evasc will iterate the design of their stent (eCLIPs) to achieve similar or improved flow effects compared to other devices. **
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