Production of Calcium Carrier Peptides from Egg Yolk Phosvitin

蛋黄卵黄高磷蛋白生产钙载体肽

• 批准号: 485627-2015
• 负责人: Sunwoo, Hoon
• 金额: $ 6.41万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=585095
• 关键词: Production; Calcium; Carrier; Peptides; Egg

We will use a new technology called high hydrostatic pressure-enzymatic hydrolysis (HHP EH) to convert phosvitin from egg yolk residue into a valuable ingredient for natural foods and calcium supplements. Phosvitin is a protein from egg yolk with 120 different binding sites for calcium, making it an excellent calcium carrier. Using HHP EH, we will cut phosvitin into smaller pieces (peptides) that still bind large amounts of calcium. These calcium carrier peptides may provide more available calcium to people when they are added to food products or taken in capsules as calcium supplements. The HHP EH technology is proven, but we must still optimize the processing conditions for phosvitin. The HHP EH processor mixes water, phosvitin and enzymes in a process like human digestion. We can control the pressure in the processor, the temperature, and the incubation time. We aim to find the optimal conditions to cut phosvitin into smaller peptides that bind the most calcium. Our research in this project will supply the required optimized HHP EH parameters and lead to a prototype commercial system. Our central commercial and economic outcomes are to supply food products based on HHP EH peptides to substantial and rapidly growing global markets. Our research will diversify Canadian agriculture by boosting demand for waste yolk from egg processing, and eventually for other low-value and underused animal products.

我们将使用一种名为高静水压酶水解 (HHP EH) 的新技术，将蛋黄残渣中的卵黄高磷蛋白转化为天然食品和钙补充剂的宝贵成分。卵黄高磷蛋白是一种来自蛋黄的蛋白质，具有 120 个不同的钙结合位点，使其成为极佳的钙载体。使用 HHP EH，我们将卵黄高磷蛋白切割成仍结合大量钙的较小碎片（肽）。当这些钙载体肽添加到食品中或作为钙补充剂服用胶囊时，可以为人们提供更多可用的钙。 HHP EH 技术已得到验证，但我们仍必须优化卵黄高磷蛋白的加工条件。 HHP EH 处理器在类似人体消化的过程中混合水、卵黄高磷蛋白和酶。我们可以控制处理器中的压力、温度和孵化时间。我们的目标是找到将卵黄高磷蛋白切割成与钙结合最多的较小肽的最佳条件。我们在该项目中的研究将提供所需的优化 HHP EH 参数，并形成一个原型商业系统。我们的核心商业和经济成果是向庞大且快速增长的全球市场供应基于 HHP EH 肽的食品。我们的研究将通过增加对鸡蛋加工废蛋黄的需求，以及最终对其他低价值和未充分利用的动物产品的需求，使加拿大农业多样化。