Improvement of GC methods for detection of trace organics in environmental samples

环境样品中痕量有机物检测气相色谱方法的改进

• 批准号: 486465-2015
• 负责人: Young, Cora
• 金额: $ 1.82万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=585619
• 关键词: Improvement; GC; methods; detection; trace

Polycyclic aromatic hydrocarbons (PAHs) are toxic chemicals that are present ubiquitously in the environment. Their concentrations in many environmental matrices are regulated in Canada to levels that cannot be detected by typical analytical methods. This project, in conjunction with AGAT Laboratories, will develop new methods for the analysis of PAHs. Gas chromatography separation with detection by mass spectrometry (GC-MS) is the standard analytical tool for PAH analysis. Using hydrogen as a carrier gas and large-volume injections, this project will address three goals: i) reducing reliance on expensive, non-renewable helium for gas chromatography analysis; ii) decreasing the analysis time for gas chromatography analyses; and iii) increasing the sensitivity of their analysis methods to achieve lower detection limits and expand sample market. New analytical methods that are more efficient and sensitive will be developed and validated for detection of PAHs in environmental samples by GC-MS. Incorporation of these new methods will improve the ability of AGAT Laboratories to detect toxic PAHs using standard laboratory equipment. This will both increase the market of AGAT Laboratories and reduce per sample costs. By increasing the sensitivity and efficiency of environmental methods for toxic, trace organics, this project will improve understanding of Canadian environmental PAH concentrations and the resulting impacts to human health.

多环芳烃(PAHs)是环境中普遍存在的有毒化学物质。 在加拿大，它们在许多环境基质中的浓度被管制到无法检测到的水平。 通过典型的分析方法。该项目将与AGAT实验室一起开发新的方法 用于多环芳烃的分析。气相色谱分离-质谱仪(GC-MS)是 多环芳烃分析的标准分析工具。使用氢气作为载气和大容量注射，这 该项目将解决三个目标：一)减少对昂贵的、不可再生的氦气的依赖 色谱分析；ii)减少用于气相色谱分析的分析时间；以及iii)增加 其分析方法的灵敏度达到了较低的检出限，扩大了样品市场。新的 将开发和验证更有效和更灵敏的分析方法来检测多环芳烃 用气相色谱-质谱法测定环境样品中的化学成分。这些新方法的结合将提高AGAT的能力 实验室使用标准实验室设备检测有毒的多环芳烃。这两个都将增加市场 阿加特实验室，降低每份样品的成本。通过提高环境保护的敏感性和效率 有毒、痕量有机物的方法，该项目将提高对加拿大环境多环芳烃的了解 浓度及其对人类健康的影响。