Gulf Coast Health Alliance: health Risks related to the Macondo Spill (GC-HARMS)

墨西哥湾沿岸健康联盟：与马孔多泄漏事件相关的健康风险 (GC-HARMS)

• 批准号: 8469037
• 负责人: Cornelis Johan Elferink
• 金额: $ 151.5万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-27 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8469037
• 关键词: Address; Affect; Ally; Animal Behavior; Aromatic Polycyclic Hydrocarbons; Basic Science; Biological; Biological Assay; Biological Markers; Cells; Charge; Clinical Investigator; Clinical Research; Collaborations; Communication; Communities; Community Health; Community Outreach; Community Participation; Concentration measurement; Consumption; DNA; Detection; Development; Disasters; Economics; Educational Intervention; Ensure; Epidemiology; Exposure to; Feedback; Fishes; Food Webs; Fostering; Future; General Population; Glucocorticoids; Goals; Harvest; Health; Health Alliance; Health Professional; Human; Hurricane; Individual; Institution; Interdisciplinary Study; Justice; Longitudinal Studies; Louisiana; Marines; Mass Spectrum Analysis; Measures; Medical; Metabolism; Methodology; Methods; Mexico; Mission; Mississippi; Modeling; Monitor; Mutagenesis; National Institute of Environmental Health Sciences; Nature; Oils; Outcome; Oxidative Stress; Participant; Pennsylvania; Plasma; Policy Maker; Population; Process; Psychosocial Stress; Quality of life; Research; Research Personnel; Research Project Grants; Resources; Risk; Risk Assessment; Risk Management; Safety; Sales; Sampling; Scientist; Seafood; Shellfish; System; Texas; Tobacco; Toxic effect; Toxicology; Translating; Translational Research; Universities; Urine; Vulnerable Populations; base; community based participatory research; design; exposed human population; foodborne; fundamental research; gulf coast; interdisciplinary approach; interest; man; meetings; member; metabolomics; outreach; programs; ranpirnase; resilience; response; skills; stressor; success

The "Gulf Coast Health Alliance: health Risks related to the Macondo Spill (GO-HARMS)" consortium will address critical concerns raised by our community partners regarding Gulf of Mexico seafood safety in the wake of the Deepwater Horizon (DWH) Disaster. The GC-HARMS consortium participants include the University of Texas Medical Branch (UTMB), the University of Pennsylvania (UPenn), Texas A&M University at Galveston (TAMUG), and Gulf Coast communities impacted by the DWH Disaster. The coalition of community partners are represented by the Louisiana Environmental Action Network (Baton Rouge, LA), the Center for Environmental and Economic Justice (Biloxi, MS), the Mississippi Coalition for Vietnamese Fishertolk (Gulfport, MS), and the United Houma Nation (Houma, LA). The mission of the GC-HARMS consortium is to explore the health impacts and community resiliency related to the DWH Disaster by fostering collaborative interactions amongst multi-disciplinary, multi-institutional basic and clinical investigators¿buttressed by active participation of the community partners¿to pursue both fundamental and translational research pertinent to the effects of the oil spill on human health. The overall theme of the GCHARMS consortium is to understand and communicate the human health risks of exposure to potentially hazardous food-borne petrogenic Polycyclic Aromatic Hydrocarbons (PAH). Our goals developed in collaboration with our community partners are to, 1) assess PAH contamination of Gulf seafood caught by the subsistence fishing communities for personal consumption and commercial sale, 2) determine the toxicity of petrogenic PAH, 3) evaluate exposure and health outcomes in a longitudinal study involving the community partners measuring multiple stressor biomarkers, and 4) disseminate the findings to our community stakeholders. To achieve these objectives, the GC-HARMS consortium is comprised of four research projects, including a Community-based Participatory Research project, a closely allied Community Outreach and Dissemination Core, and an Administrative Core. Additionally, the consortium leverages support from two NIEHS P30 Core Centers to provide essential resources.

“墨西哥湾沿岸健康联盟：与马孔多泄漏相关的健康风险（GO-HARMS）”联盟将 解决我们的社区合作伙伴在深水地平线（DWH）灾难后对墨西哥湾海鲜安全提出的严重关切。GC-HARMS联盟的参与者包括 德克萨斯大学医学分支（UTMB），宾夕法尼亚大学（UPenn），德克萨斯A&M大学加尔维斯顿（TAMUG），以及受DWH灾难影响的墨西哥湾沿岸社区。社区合作伙伴联盟由路易斯安那州环境行动网络（巴吞鲁日，路易斯安那州），环境和经济正义中心（比洛西，密西西比州），密西西比越南渔民联盟（格尔夫波特，密西西比州）和联合侯马民族（侯马，路易斯安那州）代表。GC-HARMS联合体的使命是通过促进多学科、多机构基础和临床研究人员之间的协作互动，探索与DWH灾难相关的健康影响和社区复原力，并得到社区合作伙伴积极参与的支持，以开展与漏油对人类健康影响相关的基础和转化研究。GCHARMS联盟的总体主题是了解和交流暴露于潜在危险的食源性产岩多环芳烃（PAH）的人类健康风险。我们与社区合作伙伴合作开发的目标是：1）评估由自给性渔业社区捕获的用于个人消费和商业销售的海湾海鲜的PAH污染，2）确定产岩PAH的毒性，3）在涉及社区合作伙伴测量多种压力源生物标志物的纵向研究中评估暴露和健康结果，及（四）向社会各界人士公布调查结果。为了实现这些目标，GC-HARMS联盟由四个研究项目组成，包括一个基于社区的扩展性研究项目，一个密切相关的社区外展和传播核心，以及一个行政核心。此外，该联盟还利用两个NIEHS P30核心中心的支持来提供必要的资源。