The brain-microbiome-gut axis: Do alterations in the gut microbiome effect levels of inflammation and anxious behavior in both rats and humans?

大脑-微生物组-肠道轴：肠道微生物组的改变是否会影响大鼠和人类的炎症和焦虑行为水平？

• 批准号: 349916
• 负责人: Barnett Burns Sarah
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-12-01 至 2016-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=349916&lang=en
• 关键词: Anxiety; Brain-Gut Axis; Hpa Axis; Metagenomics; Microbiome; Probiotics; Psychobiotics; Stress

We live our entire lives in close contact with a complex microbial eco-system whose collective genome outnumbers our genome by a factor of 100. It is well established that this microbiome interacts with our immune system to modulate inflammatory pathways.

我们一生都在与一个复杂的微生物生态系统密切接触，这个生态系统的集体基因组是我们基因组的100倍。众所周知，这种微生物群与我们的免疫系统相互作用，调节炎症途径。