Neural Mechanisms of Interoceptive Representation and Regulation

内感受表征和调节的神经机制

• 批准号: RGPIN-2015-05901
• 负责人: Farb, Norman
• 金额: $ 2.04万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=590709
• 关键词: Neural; Mechanisms; Interoceptive; Representation; Regulation

The human brain continuously updates representations of one’s internal body state, a process known as interoception. The long-term goals of this research program are to understand the neural mechanisms supporting interoception and how to efficiently and objectively assess interoceptive capacity. Using behavioral, psychophysiological, and functional magnetic resonance imaging (fMRI) methods, we intend to examine the psychological and neural bases for how interoception integrates physiology with cognition to inform emotional experience, and ultimately how these processes shape subjective awareness. Furthermore, we will examine whether interoceptive attention constitutes a form of arousal regulation that may be used to achieve valued physiological states. Consideration of emotion in terms of its physical, neural, and cognitive components will provide a more complete understanding of human emotion.

人类的大脑会不断更新身体内部状态的表征，这一过程被称为内感受。本研究的长期目标是了解支持内感受的神经机制，以及如何有效、客观地评估内感受能力。利用行为、心理生理学和功能磁共振成像（fMRI）方法，我们打算研究内感受如何将生理学与认知结合起来，从而为情感体验提供信息，以及这些过程最终如何塑造主观意识的心理和神经基础。此外，我们将研究内感受性注意是否构成一种唤醒调节形式，可用于实现有价值的生理状态。从生理、神经和认知的角度考虑情感，将使我们对人类情感有更全面的了解。