Novel Brain-Chip Technology Development for Mammalian Neurons

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Our research program is focused on developing novel neuron-chip and nerve-electronic conduit technologies that enable better understanding of brain function and to ensure future development of neuro-prosthesis. These novel technologies also hold tremendous potential for commercialization, which will boost Canadian economy. Specifically, we have developed four novel technologies in partnership with the Max Plank Institute (Germany – the neuro-chip), NRC (Ottawa – the patch clamp chip), Lab on Chip (Schulich School of Engineering) and a dopamine detection chip (UK). All of these technologies took advantage of large invertebrate neurons, which are easily accessible at the level of single cells and can be manipulated on these chips with great ease. Moreover, these snail neurons do not require oxygenation and temperature regulations. To advance our technology development for commercialization further, we need to explore their potential for long-term recordings from vertebrate neurons. To achieve this, we require an inverted microscope along with mounted incubator (CO