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Synaptic depression through microglia-mediated pruning in Alzheimer’s disease

Synaptic depression through microglia-mediated pruning in Alzheimer’s disease
阿尔茨海默病中小胶质细胞介导的修剪导致突触抑制
批准号：
349871
负责人：
Salter Eric W
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-12-01 至 2016-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=349871&lang=en
关键词：
Alzheimer'S Disease Electrophysiology Glutamate Hippocampus Long-Term Depression Microglia Synaptic Plasticity Synaptic Pruning Synaptic Transmission

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中文摘要
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英文摘要
Synapses are the primary sites of communication between neurons within the brain and are capable of undergoing the process of plasticity, which is a change in the strength of the synaptic connection. Alzheimer's disease (AD) is the most prevalent neurodeg
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Investigating the role of the complement cascade in NMDA receptor-dependent synaptic plasticity during hippocampus development.
  • 批准号：
    404059
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2018
  • 负责人：
    Salter Eric W
  • 依托单位：
    Sinai Health System (Toronto)
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