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Investigating the Mechanism of Extracellular Matrix Remodeling in Human Aortic Aneurysm

Investigating the Mechanism of Extracellular Matrix Remodeling in Human Aortic Aneurysm
人主动脉瘤细胞外基质重塑机制的研究
批准号：
350004
负责人：
Kang Sean
金额：
$1.27万
依托单位：
University of Calgary
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-12-01 至 2016-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=350004&lang=en
关键词：
Aneurysm Aortic Disease Cardiovascular Disease Extracellular Matrix Fibroblast Matrix Metalloproteinase Myofibroblast Transforming Growth Factor Beta Valvular Disease Vascular Remodeling

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中文摘要
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英文摘要
Bicuspid aortic valve (BAV) disease is the most commonly inherited heart defect that affects 1-2% of the general population. Patients with BAV are prone to developing aortic aneurysms that can lead to a rupture and sudden cardiac death. Aneurysms are char
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Direct effects of empagliflozin on human cardiac fibroblast-mediated extracellular matrix remodeling: Novel translational clues to EMPA-REG OUTCOME
  • 批准号：
    368340
  • 项目类别：
  • 资助金额：
    $0.07万
  • 财政年份：
    2017
  • 负责人：
    Kang Sean
  • 依托单位：
    University of Calgary
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