7th GenTAC Thoracic Aortic Disease Summit

第七届 GenTAC 胸主动脉疾病峰会

• 批准号: 10462853
• 负责人: Kim Eagle
• 金额: $ 2.54万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10462853
• 关键词: Acute; Aortic Diseases; Award; Basic Science; Belgium; Blood Vessels; COVID-19 pandemic; Cardiovascular system; Chest; China; Clinical; Clinical Sciences; Collaborations; Communication; Eagles; Engineering; Enrollment; European; Faculty; Foundations; Funding; Germany; Grant; Heart; International; Italy; Japan; Location; Marfan Syndrome; Michigan; Mission; National Heart, Lung, and Blood Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Netherlands; Paris, France; Participant; Patient Care; Patients; Physician Executives; Principal Investigator; Registries; Research; Research Personnel; Scientist; Spain; Structure; Syndrome; Thoracic Aortic Aneurysm; Time; Translational Research; Travel; Turner' s Syndrome; Underrepresented Minority; Universities; Walking; Woman; bicuspid aortic valve; career; design; experience; improved; lectures; meetings; mid-career faculty; multidisciplinary; novel; posters; programs; social; symposium; synergism; virtual

This application is in request for support for the 7th GenTAC Thoracic Aortic Disease Summit to be held in Paris, France on April 28, 2022. This unique meeting brings together multidisciplinary groups of clinicians, scientists, and engineers to advance our understanding of the underlying mechanisms of thoracic aortic disease and to improve our ability to treat those who are afflicted by these conditions, which includes both young and old. The 7th GenTAC summit for the first time will be held in collaboration 11th International Research Symposium on Marfan Syndrome (held April 24-27 at the same location) and is organized jointly with the Marfan Foundation. This shared meetings provides a forum not only where ideas are shared and scrutinized, but new collaborations are born. The biannual GenTAC conference originated in 2009 as part of the mission of the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Related Cardiovascular Conditions (GenTAC). GenTAC was funded by NHLBI and NIAMS and enrolled and followed over 3600 patients from 2006 through 2016. Gentac Alliance was initiated in 2017 to harness the synergy and collaboration created by the GenTAC. The 5th GenTAC Summit was held on Oct 6-7, 2018 at OHSU in Portland, OR and the 6th GenTAC Summit was held virtually due to the covid-19 pandemic on October 10/11 2020. The preliminary program for this 1-day GenTAC summit includes scientific sessions on (i) Familial Aortopathy, (ii) Bicuspid aortic valve, (iii) Turner Syndrome, and (iv) Acute aortic syndrome. There will be synergy with the program of the 11th Research Symposium on Marfan syndrome. We anticipate that clinicians and researcher will attend both meetings representing different groups in the field of thoracic aortic aneurysms including Marfan Foundation, IRAD, Montalcino Aortic Consortium, BAVCON, EDS-PCORI, Turners, and European Vascular Network are participating. We have >80% of invited speakers are confirmed. Participation of trainees and underrepresented minorities is especially encouraged by awarding 10 travel awards. The meeting is hosted by Marfan Foundation and the Frankel Cardiovascular Center at the University of Michigan. The core conference organization committee includes Dr. Marion A Hofmann Bowman and Dr. Kim Eagle as the principal investigators of this grant, and Dr. Josephine Grima from the Marfan Foundation. This team also successfully organized the 2020 6th GenTAC meeting. Kim A. Eagle is the Director of the Frankel Cardiovascular Center at the University of Michigan and the chair of the NHLBI sponsored GenTAC Alliance and he served as the study chair of the GenTAC registry from 2006-2016. Dr. Marion A Hofmann Bowman is a Clinical Associate Professor and Executive Medical Director of the MiAorta program at the University of Michigan. Her expertise is in clinical-translational research related to thoracic aortic disease.

本申请是为了支持将于2016年在美国纽约举行的第七届GenTAC胸主动脉疾病峰会。 2022年4月28日，法国巴黎。这次独特的会议汇集了多学科的临床医生， 科学家和工程师，以促进我们对胸主动脉疾病的潜在机制的理解 并提高我们治疗这些疾病患者的能力，包括年轻人和 老了第七届GenTAC峰会将首次与第11届国际研究研讨会合作举行 马凡氏综合症（4月24日至27日在同一地点举行），并与马凡氏基金会联合举办。 这种共享会议不仅提供了一个分享和审查想法的论坛， 出生了每年两次的Gentac会议起源于2009年，是国家登记处使命的一部分。 遗传性触发的胸主动脉瘤和相关心血管疾病（GenTAC）。GenTAC 由NHLBI和NIAMS资助，从2006年到2016年招募并随访了3600多名患者。根塔克 联盟于2017年启动，旨在利用GenTAC创造的协同效应和协作。第五届Gentac 峰会于2018年10月6日至7日在俄勒冈州波特兰的OHSU举行，第六届GenTAC峰会几乎如期举行 2020年10月10日至11日的新冠肺炎疫情。 为期一天的GenTAC峰会的初步计划包括以下方面的科学会议：（i）家族性主动脉病， (ii)二叶式主动脉瓣，（iii）特纳综合征，和（iv）急性主动脉综合征。将与 第11届马凡氏综合征研究研讨会我们希望临床医生和研究人员 代表包括Marfan在内的胸主动脉瘤领域的不同小组参加这两次会议 基金会、IRAD、Montalcino主动脉联盟、BAVCON、EDS-PCRI、Turners和欧洲血管 网络参与。我们有超过80%的受邀演讲者被确认。受训人员的参与和 颁发10项旅行奖尤其令代表性不足的少数族裔受到鼓舞。 会议由马凡基金会和弗兰克尔心血管中心在大学主办。 密歇根核心会议组织委员会包括马里恩·霍夫曼·鲍曼博士和金博士 鹰作为这项赠款的主要研究人员，和约瑟芬格里马博士从马凡基金会。这 团队还成功组织了2020年第六届GenTAC会议。Kim A.鹰是弗兰克尔的主任 密歇根大学心血管中心和NHLBI赞助的GenTAC联盟主席 他在2006-2016年期间担任GenTAC登记研究的研究主席。马里恩·霍夫曼·鲍曼博士是一位 临床副教授和执行医学主任的MiAorta计划在大学 密歇根她的专业知识是与胸主动脉疾病相关的临床转化研究。