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Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues

Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues
使用视频力显微镜 (VFM) 确定驱动细胞和组织形态发生运动的力
批准号：
36514-2012
负责人：
Brodland, Wayne
金额：
$2.26万
依托单位：
University of Waterloo
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-01-01 至 2017-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=593015
关键词：
UsingvideoforcemicroscopyVFM

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英文摘要
Most people do not realize how important cell and tissue movements are to human health. However, it is through such movements that organs and other critical structures form during early embryo development, that wounds heal, that cells leave a primary cancer tumour and establish metastases, and that proper structure and function arise in engineered tissues. These movements are driven by sub-cellular structural components, and alterations to the forces they generate can significantly impact health outcomes. One could conceive pharmaceutical and other means to therapeutically manipulate these forces, but we must have practical ways to measure them if we are to evaluate proposed interventions, and that is the goal of my research program.
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Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues
  • 批准号：
    36514-2012
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.26万
  • 财政年份：
    2015
  • 负责人：
    Brodland, Wayne
  • 依托单位：
    University of Waterloo
Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues
  • 批准号：
    36514-2012
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.26万
  • 财政年份：
    2014
  • 负责人：
    Brodland, Wayne
  • 依托单位：
    University of Waterloo
Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues
  • 批准号：
    36514-2012
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.26万
  • 财政年份：
    2013
  • 负责人：
    Brodland, Wayne
  • 依托单位：
    University of Waterloo
Using video force microscopy (VFM) to determine the forces that drive morphogenetic movements of cells and tissues
  • 批准号：
    36514-2012
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.26万
  • 财政年份：
    2012
  • 负责人：
    Brodland, Wayne
  • 依托单位：
    University of Waterloo
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