The Aging Brain: Circadian, Transcriptomic, and Epigenomic Dimensions

大脑老化：昼夜节律、转录组和表观基因组维度

• 批准号: 344857
• 负责人: Petronis Arturas
• 金额: $ 79.09万
• 依托单位: Centre for Addiction and Mental Health (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2019-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=344857&lang=en
• 关键词: Aging; Alzheimer'S Disease; Brain; Circadian; Dna Modification; Epigenome; Transcriptome

One of the most important questions of biomedical research is "why do we ail as we age?". This may be in part due to a breakdown of the body's circadian rhythm - the physiological process that tunes up or down various bodily functions during the 24 hr cyc

生物医学研究中最重要的问题之一是“为什么我们会随着年龄的增长而生病？".这可能部分是由于身体的昼夜节律的崩溃-在24小时循环中调节各种身体功能的生理过程。