Spatiotemporal Dynamics of Chromatin: the Circadian and Aging Connection

染色质的时空动态：昼夜节律与衰老的联系

• 批准号: 365582
• 负责人: Petronis Arturas
• 金额: $ 58.28万
• 依托单位: Centre for Addiction and Mental Health (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-02-01 至 2020-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=365582&lang=en
• 关键词: Aging; Chromatin; Circadian; Histones; Nucleome; Spatial And Temporal Dimension; Transcription

This project is dedicated to understanding of how genes are regulated in the cell's nucleus. We will investigate not only spatial parameters of such regulation but also temporal ones: how molecules surrounding DNA change during the 24 hour period (circadi

该项目致力于了解基因在细胞核中的调节方式。我们将不仅研究这种调节的空间参数，而且研究时间参数：DNA周围的分子在24小时内如何变化（circadi