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Control of ER-mitochondria contacts and mitophagy by the Gp78 ubiquitin ligase: Role in tumor progression

Control of ER-mitochondria contacts and mitophagy by the Gp78 ubiquitin ligase: Role in tumor progression
Gp78 泛素连接酶控制 ER 线粒体接触和线粒体自噬:在肿瘤进展中的作用
批准号:
344557
负责人:
Nabi Ivan R
金额:
$77.97万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01

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中文摘要
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英文摘要
Select breast cancers and certain other cancers are difficult to treat, resulting in devastating prognostic outcomes. Autocrine motility factor (AMF) and its receptor, Gp78 (also known as AMFR), are linked to malignancy in various cancers. However, Gp78 h
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Role of MERCs and Mitophagy in Cancer Progression
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    462041
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  • 资助金额:
    $69.38万
  • 财政年份:
    2022
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Using super-resolution microscopy to define the role of caveolin-1 in cancer
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    433430
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    2020
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Super-resolution microscopy network analysis: Drug target validation for cystic fibrosis
  • 批准号:
    396257
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    $28.44万
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    2018
  • 负责人:
    Nabi Ivan R
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Caveolin-1 regulation of focal adhesion tension and the breast cancer cell response to matrix stiffness
  • 批准号:
    387239
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    Operating Grants
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  • 依托单位:
海外基金