Investigating the mode of action of novel eco-friendly cell-free microbial bioproducts for improving plant growth, productivity and stress tolerance

研究新型环保无细胞微生物生物制品改善植物生长、生产力和抗逆性的作用方式

• 批准号: 484831-2015
• 负责人: Rothstein, Steven
• 金额: $ 3.64万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=600032
• 关键词: Investigating; mode; action; novel; eco

TerraBioGen (TBG) Technologies, a small agricultural biotechnology company based at Burnaby, British Columbia are developing agricultural bioproducts based on metabolites and signal molecules produced by a unique group of naturally occurring microorganisms. Early studies with different plant species under varied growth conditions showed that application of TerraBioGen's products improved seed germination and seedling emergence, imparted a robust root system, enhanced plant growth and health and increased crop yield and crop quality under high and low fertilizer regimes as well as under water stress conditions. For commercial success, the scientific basis and modes of action of metabolites are needed and the proposed research is a collaboration between TerraBioGen researchers and with the Rothstein laboratory at the University of Guelph to unravel the modes of action of TerraBioGen's bioproducts. The TerraBioGen researchers will be studying microbial strains that they have identified that produce the growth promoting factors and developing methods for scaling production, isolating and identifying the bioactive materials and doing initial tests on these for plant growth enhancement. The Rothstein laboratory will study the effect of these crude as well as pure cell-free metabolic products on growth in corn in both stress and non-stress conditions. They will study whether the addition of these compounds improves the plants ability to use water and nutrients efficiently. In addition, they will analyze the expression of all of the genes using genomic analysis to understand how these compounds work to effect crop growth. This work can be used by TerraBioGen for the development of their technology to assess how and when they should be applied to crop plants as well as to identify new bioactive compounds. Success in this will be fundamental for their success in producing products that can improve Canadian crop production in an environmentally sensitive fashion as well as being able to sell these in the international markets.

一家位于不列颠哥伦比亚省本那比的小型农​​业生物技术公司Terrabiogen（TBG）技术正在基于代谢物和信号分子开发农业生物生物产生，由独特的自然发生的微生物产生。在不同生长条件下，对不同植物物种的早期研究表明，田纳比原料的应用改善了种子发芽和幼苗的出现，赋予了健壮的根系，增强了植物生长和健康，以及在高肥料方案以及水应力条件下的作物产量和作物质量提高。为了获得商业成功，需要进行科学基础和代谢物的作用方式，拟议的研究是Terrabiogen研究人员与圭尔夫大学的Rothstein实验室之间的合作，以揭示Terrabiogen生物生物生物产品的作用模式。 Terrabiogen研究人员将研究他们确定的微生物菌株，这些微生物菌株产生了促进生长因素并开发用于扩展生产，隔离和鉴定生物活性材料的方法，并对这些材料进行初步测试以增强植物生长。 Rothstein实验室将研究这些原油以及无细胞的代谢产物对压力和无压力条件下玉米生长的影响。他们将研究这些化合物的添加是否可以提高植物有效使用水和养分的能力。此外，他们将使用基因组分析分析所有基因的表达，以了解这些化合物如何作用作物生长。 Terrabiogen可以将这项工作用于开发其技术，以评估应如何以及何时将其应用于作物植物以及鉴定新的生物活性化合物。成功的成功将是他们成功生产可以以环境敏感的方式改善加拿大作物生产的产品以及能够在国际市场上出售这些产品的基础。