Inflammasome regulatory mechanisms in health and inflammatory diseases

健康和炎症疾病中的炎症小体调节机制

• 批准号: 342613
• 负责人: Saleh Maya
• 金额: $ 68.5万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2021-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=342613&lang=en
• 关键词: Cell Death; Inflammation; Innate Immunity; Mitochondria; Ubiquitination

The innate immune system is our first line of defense against microbial invasion, tissue injury and cellular transformation. Among its arsenals are evolutionary conserved sensors of danger signals named inflammasomes that defend the organism from pathogen

先天免疫系统是我们抵御微生物入侵、组织损伤和细胞转化的第一道防线。在它的武器库中，有进化保守的危险信号传感器，称为炎症体，可以保护有机体免受病原体的侵害。