Targeting key regulators of innate immunity in inflammation-associated cancer
Targeting key regulators of innate immunity in inflammation-associated cancer
批准号:
nhmrc : GNT1154279
负责人:
Prof Brendan Jenkins
金额:
$64.92万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
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英文摘要
Uncontrolled regulation of the immune system promotes inflammation-associated pancreatic, stomach and lung cancers, which are among the most common cancers worldwide. The high death rate of these cancers is largely due to late detection at advanced stages, along with the ineffectiveness of current therapies. My project aims to identify key regulators of the immune system as novel molecular biomarkers (e.g. for early detection) and targets for personalised treatments in these diseases.
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会议论文
Novel role of inflammasomes in the molecular pathogenesis of emphysema
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批准号:nhmrc : GNT1139373
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项目类别:Project Grants
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资助金额:$76.45万
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财政年份:2018
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负责人:Prof Brendan Jenkins
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依托单位:
Novel role of inflammasomes in the molecular pathogenesis of emphysema
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批准号:nhmrc : 1139373
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项目类别:Project Grants
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资助金额:$51.69万
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财政年份:2018
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负责人:Prof Brendan Jenkins
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依托单位:
Novel role of innate immune DNA sensors in promoting gastric cancer
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批准号:nhmrc : 1139371
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项目类别:Project Grants
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资助金额:$52.33万
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财政年份:2018
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负责人:Prof Brendan Jenkins
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依托单位:
Novel role of innate immune DNA sensors in promoting gastric cancer
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批准号:nhmrc : GNT1139371
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项目类别:Project Grants
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资助金额:$77.4万
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财政年份:2018
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负责人:Prof Brendan Jenkins
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依托单位:
The molecular basis by which the interleukin-6 cytokine promotes emphysema
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批准号:nhmrc : 1079475
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项目类别:Project Grants
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资助金额:$43.97万
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财政年份:2015
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负责人:Prof Brendan Jenkins
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依托单位:
The molecular basis by which IL-6 family cytokines and pathogen recognition receptors promote inflammation-associated stomach and lung cancer
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批准号:nhmrc : 1058261
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项目类别:Research Fellowships
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资助金额:$42.08万
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财政年份:2014
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负责人:Prof Brendan Jenkins
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依托单位:
Identification of interleukin-6 trans-signalling as a novel target for therapeutic approaches to lung cancer
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批准号:nhmrc : 1063998
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项目类别:Project Grants
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资助金额:$41.81万
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财政年份:2014
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负责人:Prof Brendan Jenkins
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依托单位:
IL-6 family cytokines and pathogen recognition receptors in inflammation-associated cancer
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批准号:nhmrc : GNT1058261
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项目类别:Research Fellowships
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资助金额:$60.14万
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财政年份:2014
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负责人:Prof Brendan Jenkins
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依托单位:
Deregulated cytokine signalling as a molecular bridge linking the pathogenesis of emphysema to lung cancer.
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批准号:nhmrc : 1003605
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项目类别:NHMRC Project Grants
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资助金额:$35.0万
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财政年份:2011
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负责人:Prof Brendan Jenkins
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依托单位:
Genetic approaches to understand how imbalanced cytokine signalling drives the pathogenesis of emphysema
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批准号:nhmrc : 490957
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项目类别:NHMRC Project Grants
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资助金额:$34.65万
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财政年份:2008
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负责人:Prof Brendan Jenkins
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依托单位:
The Opposing Roles of STAT1 and STAT3 Signalling by IL-6 Family Cytokines in Inflammation and Tumourigenesis
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批准号:nhmrc : 384268
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项目类别:NHMRC Project Grants
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资助金额:$31.52万
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财政年份:2006
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负责人:Prof Brendan Jenkins
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依托单位:
The opposing roles of STAT1 & STAT3 signalling elicited byIL-6 family cytokines in cancer & inflammation.
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批准号:nhmrc : 384219
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项目类别:Career Development Fellowships
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资助金额:$18.14万
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财政年份:2006
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负责人:Prof Brendan Jenkins
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依托单位:
国内基金
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