Catalytic synthesis of specialty chemicals from sustainable resources

利用可持续资源催化合成特种化学品

• 批准号: 493863-2016
• 负责人: Chin, YaHueiCathy
• 金额: $ 9.03万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Strategic Projects - Group
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=602901
• 关键词: Catalytic; synthesis; specialty; chemicals; sustainable

Green synthesis of commodity, specialty, and pharmaceutical chemicals from renewable feedstocks is one of the Grand Challenges of 21st century. The proposed work will develop new catalytic strategies combining the broad spectrum of knowledge from chemistry, chemical engineering, and materials engineering. We will adapt a multidisciplinary approach, integrating material discovery and characterizations, chemical kinetic tuning, reaction engineering, and chemical process optimization to manipulate the fate of the oxygenates, derived from lignocellulosic biomass abundant from Canada's forest and agricultural sectors, as they undergo catalytic transformation in the condensed phase to value-added chemicals, pharmaceuticals, and polymer precursors. We will accomplish our pursuit by establishing the catalytic events at the level of atoms and electrons, understanding the connection of these events to the thermochemical properties of the reactants, the reaction media, and the catalyst complexes/surfaces and then applying the knowledge in order to manipulate the reaction pathways for a series of cascade reactions. These cascade reactions occur in separate media (protic/aprotic solvent) and require different local site and coordination environments, but our goal is to tune the reactivities such that they occur concomitantly and efficiently at the molecular length scales and in one pot. Incorporating in this research program is a comprehensive professional training program, which places strong emphasis to technical and leadership trainings of the highly qualified personnel (HQP). The HQP will acquire diverse skill sets and industrial and global perspective, through direct interactions with our industrial partners and collaborators and exposure to world class instrumentation. The personnel with these skill sets are much needed in Canadian energy and chemical industries to ensure that Canada remains competitive at the global stage.

以可再生原料为原料生产日用化学品、特种化学品和医药化学品的绿色合成是世纪的重大挑战之一。拟议的工作将结合化学，化学工程和材料工程的广泛知识开发新的催化策略。我们将采用多学科的方法，整合材料发现和表征，化学动力学调整，反应工程和化学工艺优化，以操纵含氧化合物的命运，这些含氧化合物来自加拿大森林和农业部门丰富的木质纤维素生物质，因为它们在凝聚相中经历催化转化，成为增值化学品，药物和聚合物前体。我们将通过在原子和电子水平上建立催化事件来实现我们的追求，了解这些事件与反应物，反应介质和催化剂络合物/表面的热化学性质的联系，然后应用知识来操纵一系列级联反应的反应途径。这些级联反应发生在不同的介质（质子/非质子溶剂），需要不同的本地网站和协调环境，但我们的目标是调整的反应性，使它们同时发生，有效地在分子长度尺度和在一锅。该研究计划是一项全面的专业培训计划，重点强调高素质人员（HQP）的技术和领导力培训。HQP将通过与我们的工业合作伙伴和合作者的直接互动以及接触世界一流的仪器仪表来获得多样化的技能组合以及工业和全球视角。加拿大能源和化学工业急需具有这些技能的人员，以确保加拿大在全球舞台上保持竞争力。