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Assembly, activation and function of BRISC deubiquitinase complexes

Assembly, activation and function of BRISC deubiquitinase complexes
BRISC 去泛素酶复合物的组装、激活和功能
批准号:
358787
负责人:
Daou Salima
金额:
$10.2万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-09-01 至 2018-09-01

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中文摘要
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英文摘要
Our cells dispose of damaged proteins using a highly sophisticated protein degradation system. However, abnormalities in the protein degradation system are frequently observed in many diseases, including several types of cancers and auto-immune disorders.
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Structural basis and mechanism of BAP1 ubiquitination and tumor suppressor regulation by the E2/E3 hybrid enzyme UBE2O
  • 批准号:
    440448
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $3.28万
  • 财政年份:
    2020
  • 负责人:
    Daou Salima
  • 依托单位:
Assembly, activation and function of BRISC deubiquitinase complexes
  • 批准号:
    361711
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $9.83万
  • 财政年份:
    2016
  • 负责人:
    Daou Salima
  • 依托单位:
海外基金