Improved model of aging: genetic induction of oxidative stress in PolG mutator mice
Improved model of aging: genetic induction of oxidative stress in PolG mutator mice
改进的衰老模型：PolG 突变小鼠氧化应激的遗传诱导
批准号：
179958
负责人：
Tarnopolsky Mark A
金额：
$3.57万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2010-03-01
中文摘要
翻译
人类的衰老与肌肉萎缩和虚弱有关，这可能会损害功能独立性。来自老年人的骨骼肌显示出氧化应激(自由基过量)和线粒体功能障碍(细胞的“动力库”)的证据。
英文摘要
Human aging is associated with muscle atrophy and weakness that can impair functional independence. Skeletal muscle from older adults shows evidence of oxidative stress (free radical excess) and mitochondrial dysfunction (the "powerhouse" of the cell).
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海外基金
