Fragment-based screening approaches for new antibiotics directed against the bacterial sliding clamp

针对细菌滑动钳的新型抗生素的基于片段的筛选方法

• 批准号: DP110100660
• 负责人: A/Prof Aaron Oakley
• 金额: $ 21.11万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110100660
• 关键词: Fragment; based; screening; approaches; new

This project will use new approaches to develop a new generation of effective antibacterial agents to combat rising resistance in key pathogens. The project will target DNA replication and repair processes that are essential for bacterial survival and proliferation.

该项目将采用新方法开发新一代有效抗菌剂，以对抗关键病原体日益增长的耐药性。该项目将以细菌生存和增殖所必需的DNA复制和修复过程为目标。