Synthesis, Stereochemistry and Catalysis in Organosulfur Chemistry

有机硫化学中的合成、立体化学和催化

基本信息

  • 批准号:
    RGPIN-2015-05424
  • 负责人:
  • 金额:
    $ 2.55万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Individual
  • 财政年份:
    2016
  • 资助国家:
    加拿大
  • 起止时间:
    2016-01-01 至 2017-12-31
  • 项目状态:
    已结题

项目摘要

Every inventor requires a background database of knowledge from which he/she draws information. That information is combined with the inventor's idea, imagination and skill to produce a new process or product. If the database of information was not able to grow, inventors would soon run out of new intellectual "raw materials" that are so essential to the inventive puzzle. In time, our society would no longer be economically, technologically or culturally progressive. In the chemical field, inventions often include new pharmaceuticals, materials, food products and new products for the home and farm. Inventions could also include new processes to produce established products by substantially more economical and/or environmentally friendly methods. The chemistry database contains, for example, information regarding fundamental chemical reactions and theories of bonding in chemistry. Often, a researcher contributing to the database is unable to predict when or how their information will be utilized in new chemical inventions. The investigations proposed will expand the knowledge pertaining to reactions of sulfur containing compounds. The broad projects are as follows: 1. The proposed chemistry will expand our knowledge of how existing bonding attachments (stereochemistry) of molecules result during the formation of carbon-sulfur and carbon-nitrogen bonds. It is expected that new stereochemical environments will be found, providing additional tools to the organic chemistry community. 2. We are proposing the preparation of selected biologically important sulfur containing compounds. Two of these compounds are important to understanding the biosynthesis of rare amino acids. Access to these compounds will permit biochemists to quickly gather information about how enzyme are able to function. The other target is the sulfur containing component of shiitake mushroom that impart flavours when the mushroom is cooked. Its preparation should permit increased understanding of its chemical conversions to the flavours of the mushroom. 3. We propose to expand our already established sulfur chemistry tools to create new ligands. Ligands are compounds that can facilitate metal-catalyzed carbon-carbon bond forming reactions in a myriad of reactions. We will then be in a position to follow our ligand preparation and execute those carbon-carbon bond forming reactions so molecules can be constructed special stereochemical features.
每个发明家都需要一个知识背景数据库,他/她从中提取信息。这些信息与发明者的想法、想象力和技能相结合,产生了一种新的工艺或产品。如果信息数据库不能增长,发明家们很快就会耗尽新的智力“原材料”,而这些原材料对创造性的难题至关重要。随着时间的推移,我们的社会将不再是经济、技术或文化上的进步。在化学领域,发明通常包括新的药物,材料,食品和新产品的家庭和农场。发明还可以包括新工艺 以通过实质上更经济和/或环境友好的方法来生产成熟的产品。化学数据库包含例如关于化学中的基本化学反应和成键理论的信息。通常,为数据库做出贡献的研究人员无法预测他们的信息何时或如何被用于新的化学发明。 提出的调查将扩大有关含硫化合物的反应的知识。主要项目如下: 1.提出的化学将扩大我们的知识,如何现有的键连接(立体化学)的分子在形成碳-硫和碳-氮键的结果。预计将发现新的立体化学环境,为有机化学界提供额外的工具。 2.我们建议选择生物重要的含硫化合物的制备。其中两种化合物对了解稀有氨基酸的生物合成很重要。获得这些化合物将使生物化学家能够快速收集有关酶如何发挥作用的信息。另一个目标是香菇中的含硫成分,当蘑菇被烹饪时,该成分赋予风味。它的制备应允许增加了解其化学转化为蘑菇的味道。 3.我们建议扩展我们已经建立的硫化学工具,以创建新的配体。配体是可以在无数反应中促进金属催化的碳-碳键形成反应的化合物。然后,我们将能够按照我们的配体制备和执行这些碳-碳键形成反应,使分子可以构建特殊的立体化学特征。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Schwan, Adrian其他文献

Schwan, Adrian的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Schwan, Adrian', 18)}}的其他基金

Explorations in Organosulfur Chemistry
有机硫化学探索
  • 批准号:
    RGPIN-2020-04029
  • 财政年份:
    2022
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Explorations in Organosulfur Chemistry
有机硫化学探索
  • 批准号:
    RGPIN-2020-04029
  • 财政年份:
    2021
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Explorations in Organosulfur Chemistry
有机硫化学探索
  • 批准号:
    RGPIN-2020-04029
  • 财政年份:
    2020
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Synthesis, Stereochemistry and Catalysis in Organosulfur Chemistry
有机硫化学中的合成、立体化学和催化
  • 批准号:
    RGPIN-2015-05424
  • 财政年份:
    2019
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Synthesis, Stereochemistry and Catalysis in Organosulfur Chemistry
有机硫化学中的合成、立体化学和催化
  • 批准号:
    RGPIN-2015-05424
  • 财政年份:
    2018
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Synthesis, Stereochemistry and Catalysis in Organosulfur Chemistry
有机硫化学中的合成、立体化学和催化
  • 批准号:
    RGPIN-2015-05424
  • 财政年份:
    2017
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Synthesis, Stereochemistry and Catalysis in Organosulfur Chemistry
有机硫化学中的合成、立体化学和催化
  • 批准号:
    RGPIN-2015-05424
  • 财政年份:
    2015
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Synthetic and mechanistic organosulfur chemistry
有机硫的合成和机械化学
  • 批准号:
    46764-2010
  • 财政年份:
    2014
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual
Development of an efficient and environmentally friendly process for production of Buproprion
开发高效且环保的安非他酮生产工艺
  • 批准号:
    477709-2014
  • 财政年份:
    2014
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Engage Grants Program
Synthetic and mechanistic organosulfur chemistry
有机硫的合成和机械化学
  • 批准号:
    46764-2010
  • 财政年份:
    2013
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Grants Program - Individual

相似海外基金

CAREER: Elliptic Dichroism Microscopy for Cellular Stereochemistry Analysis
职业:用于细胞立体化学分析的椭圆二色显微镜
  • 批准号:
    2401151
  • 财政年份:
    2023
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Continuing Grant
CAREER: Elliptic Dichroism Microscopy for Cellular Stereochemistry Analysis
职业:用于细胞立体化学分析的椭圆二色显微镜
  • 批准号:
    2236885
  • 财政年份:
    2023
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Continuing Grant
Sulfonimidamides: New Frontiers in Stereochemistry and Functionality
磺酰亚胺:立体化学和功能性的新领域
  • 批准号:
    2247324
  • 财政年份:
    2023
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Standard Grant
Dearomatization of Planar Aromatic Cores into Three-Dimensional Scaffolds with Defined Stereochemistry
平面芳香核脱芳构化成具有明确立体化学的三维支架
  • 批准号:
    10464808
  • 财政年份:
    2022
  • 资助金额:
    $ 2.55万
  • 项目类别:
Dearomatization of Planar Aromatic Cores into Three-Dimensional Scaffolds with Defined Stereochemistry
平面芳香核脱芳构化成具有明确立体化学的三维支架
  • 批准号:
    10700834
  • 财政年份:
    2022
  • 资助金额:
    $ 2.55万
  • 项目类别:
Chiral synthetic macromolecules - control of sequence and stereochemistry
手性合成大分子 - 序列和立体化学的控制
  • 批准号:
    DP210101904
  • 财政年份:
    2021
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Discovery Projects
Determining the lipid-stereochemistry specificities of Daptomycin and A54145D
确定达托霉素和 A54145D 的脂质立体化学特异性
  • 批准号:
    534766-2019
  • 财政年份:
    2021
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Doctoral
NMR, Computation and Total Synthesis; Uncovering the Stereochemistry of 1,5-polyol-containing Macrolides
核磁共振、计算和全合成;
  • 批准号:
    2625066
  • 财政年份:
    2021
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Studentship
Determining the lipid-stereochemistry specificities of Daptomycin and A54145D
确定达托霉素和 A54145D 的脂质立体化学特异性
  • 批准号:
    534766-2019
  • 财政年份:
    2020
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Doctoral
Impact of sand biofilter reactor process conditions on the stereochemistry, biological potency and treatment of micropollutants, pharmaceuticals and p
砂生物滤池反应器工艺条件对微污染物、药物和产品的立体化学、生物效力和处理的影响
  • 批准号:
    2269142
  • 财政年份:
    2019
  • 资助金额:
    $ 2.55万
  • 项目类别:
    Studentship
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了