Maintaining Ultracentrifugation Capacity for Biological Research at the Ontario Veterinary College

要求NSERC提供资金，以购买最先进的 超离心和转子，以保持核心超离心能力， 病理生物学系和安大略兽医学院。设备 要求包括Beckman BioSafe Optima XPN-90超浓缩凝胶，三个 超高速转子和4年的服务合同作为保证访问 所需的基本核心研究设备至关重要， 在该部门的计划，服务合同在最初的4年期间 包含在本申请中。随后，服务和维护费用 将由病理生物学系负责该部还将 将技术人员工资的一部分用于离心机设备 维修和HQP培训。我们先进的超精密设备 使我们处于危险的境地， ultracenthouge（无服务合同）和两个超转子。用于 该部门的研究计划严重依赖于获得基本的 超浓缩设备，它不能强调不够， 所要求的设备是为了我们的研究计划的持续成功， 我们培养的众多HQP无法获得拟议的 基础设施将对我们的发展和增长产生负面影响 研究项目。所要求的超级电容器和转子绝对 对于我们的病毒学和病毒免疫学的持续全面运作至关重要 实验室和培训我们的HQP。

Funds are requested from NSERC to purchase a state-of the-art ultracentrifuge and rotors to maintain core ultracentrifugation capacity within the department of Pathobiology and the Ontario Veterinary College. Equipment requested includes a Beckman BioSafe Optima XPN-90 ultracentrifuge, three ultra-speed rotors and a 4-year service contract. As guaranteed access to the essential core research equipment requested is critical a majority of research programs in the department, a service contract during the initial 4-year period is included in this application. Subsequently, service and maintenance costs will be covered by the Department of Pathobiology. The department will also contribute a portion of a technician’s salary for centrifuge equipment maintenance and HQP training. The advanced age of our ultracentrifuge equipment has left us in the precarious position of having only one functional ultracentrifuge (with no service contract) and two ultra-rotors. For a department whose research programs depend heavily on access to basic ultracentrifugation equipment, it cannot be emphasized enough how critical the requested equipment is for the continued success of our research programs and the numerous HQP that we train. Inability to acquire the proposed infrastructure will negatively impact the development and growth of our research programs. The ultracentrifuge and rotors requested are absolutely critical for the continuous full operation of our virology and viral immunology laboratories and for training of our HQP.