Microfluidic point-of-care immunoassay

微流控床旁免疫分析

• 批准号: 508308-2016
• 负责人: Ma, Hongshen
• 金额: $ 13.85万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=618551
• 关键词: Microfluidic; point; care; immunoassay

Point-of-care tests are medical diagnostic tests performed outside of clinical laboratories and in close proximity of patients receiving care, such as at homes, doctor's offices, and emergency departments in hospitals. The ability to perform diagnostic tests without requiring sophisticated laboratory equipment and infrastructure is important for many health conditions including cancer, heart disease, and viral infections. This proposal aims to develop a new technology to perform point-of-care diagnostic tests utilizing methods developed for manufacturing silicon microchips, which can be adapted to enable precise control over the flow of extremely small volumes of liquid. This capability enables sophisticated biochemical analyses to be performed in portable, low-cost, and automated system, which can be utilized by patients and care providers at the point of care.

医疗点测试是在临床实验室之外和在接受治疗的患者附近，如在医院的家庭、医生办公室和急诊科进行的医疗诊断测试。在不需要复杂的实验室设备和基础设施的情况下进行诊断测试的能力对于包括癌症、心脏病和病毒感染在内的许多健康状况非常重要。这项提议旨在开发一种新技术，利用为制造硅微芯片开发的方法来执行护理点诊断测试，这种方法可以被调整为能够精确控制极少量液体的流动。这一能力使复杂的生化分析能够在便携式、低成本和自动化系统中执行，患者和护理人员可以在护理点使用该系统。