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Computational systems biology: understanding mammalian cell fates using genome-scale network models

Computational systems biology: understanding mammalian cell fates using genome-scale network models
计算系统生物学:使用基因组规模网络模型了解哺乳动物细胞的命运
批准号:
DP110103384
负责人:
Prof Mark Ragan
金额:
$23.9万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-03-31

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中文摘要
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英文摘要
Mutations can disrupt the cellular networks that control normal development, causing cells to develop abnormally including in ways that lead to cancer. The project will analyse genome sequences from more than 700 pancreatic cancers and matched controls to precisely map the causative trail from mutations to disrupted networks to altered cell development.
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A multi-omics platform for molecular evolution and developmental biology
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