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The role of spatial and temporal regulation of Extracellular Matrix composition by Matrix Metalloproteases during development, growth and aging of the Drosophila heart

The role of spatial and temporal regulation of Extracellular Matrix composition by Matrix Metalloproteases during development, growth and aging of the Drosophila heart
基质金属蛋白酶对果蝇心脏发育、生长和衰老过程中细胞外基质组成的时空调节的作用
批准号:
RGPIN-2017-05348
负责人:
Jacobs, JRoger
金额:
$2.91万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
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英文摘要
The aim of this proposal is to reveal the mechanisms of cell-to-extracellular matrix (ECM) interaction that regulate development and reshaping of organs like the heart. The ECM is a network of glycoproteins and proteoglycans that are the substrate that bears cell and tissue tension, which also protects tissues and provides a source of molecules that instruct the behavior of cells.
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The role of spatial and temporal regulation of Extracellular Matrix composition by Matrix Metalloproteases during development, growth and aging of the Drosophila heart
  • 批准号:
    RGPIN-2017-05348
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.83万
  • 财政年份:
    2021
  • 负责人:
    Jacobs, JRoger
  • 依托单位:
The role of spatial and temporal regulation of Extracellular Matrix composition by Matrix Metalloproteases during development, growth and aging of the Drosophila heart
  • 批准号:
    RGPIN-2017-05348
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2020
  • 负责人:
    Jacobs, JRoger
  • 依托单位:
Campus-wide Optical Coherence Tomography Facility
  • 批准号:
    RTI-2021-00419
  • 项目类别:
    Research Tools and Instruments
  • 资助金额:
    $10.81万
  • 财政年份:
    2020
  • 负责人:
    Jacobs, JRoger
  • 依托单位:
The role of spatial and temporal regulation of Extracellular Matrix composition by Matrix Metalloproteases during development, growth and aging of the Drosophila heart
  • 批准号:
    RGPIN-2017-05348
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2019
  • 负责人:
    Jacobs, JRoger
  • 依托单位:
国内基金
海外基金
高铁对欠发达省域国土空间协调(Spatial Coherence)影响研究与政策启示-以江西省为例
  • 批准号:
    52368007
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    32万元
  • 批准年份:
    2023
  • 负责人:
    刘莉文
  • 依托单位:
发展基因编码的荧光探针揭示趋化因子CXCL10的时空动态及其调控机制
高铁影响空间失衡(Spatial Inequality)的多尺度变异机理的理论和实证研究
  • 批准号:
    51908258
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2019
  • 负责人:
    刘莉文
  • 依托单位:
考虑外源变量的空间copula插值模型的开发及其在降雨和地下水水质插值上的验证
  • 批准号:
    41101020
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    28.0万元
  • 批准年份:
    2011
  • 负责人:
    刘敏
  • 依托单位: