Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
基本信息
- 批准号:RGPIN-2017-06491
- 负责人:
- 金额:$ 2.91万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Opi1 is an amphipathic transcriptional repressor that regulates phospholipid synthesis. Phosphatidic acid (PA) is a phospholipid biosynthetic intermediate whose level in the endoplasmic reticulum (ER) regulate Opi1 ER binding. Upon release from the ER Opi1 enters the nucleus where is acts as a transcriptional repressor of a plethora of phospholipid biosynthetic genes.
Opi1是一种调节磷脂合成的两亲性转录抑制因子。磷脂酸(PA)是一种磷脂生物合成中间体,其在内质网(ER)中的水平调节Opi1 ER结合。从ER释放后,Opi 1进入细胞核,在那里作为过多磷脂生物合成基因的转录抑制因子。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
McMaster, Christopher其他文献
A Machine-Learning Algorithm to Optimise Automated Adverse Drug Reaction Detection from Clinical Coding
- DOI:
10.1007/s40264-018-00794-y - 发表时间:
2019-06-01 - 期刊:
- 影响因子:4.2
- 作者:
McMaster, Christopher;Liew, David;Frauman, Albert - 通讯作者:
Frauman, Albert
Artificial Intelligence and Deep Learning for Rheumatologists.
- DOI:
10.1002/art.42296 - 发表时间:
2022-12 - 期刊:
- 影响因子:13.3
- 作者:
McMaster, Christopher;Bird, Alix;Liew, David F. L.;Buchanan, Russell R.;Owen, Claire E.;Chapman, Wendy W.;Pires, Douglas E., V - 通讯作者:
Pires, Douglas E., V
Diagnosis of septic arthritis in the acute care setting: the value of routine intra-operative sample culture.
- DOI:
10.1093/rap/rkad008 - 发表时间:
2023-04 - 期刊:
- 影响因子:3.1
- 作者:
Shamdasani, Pallavi;Liew, David F. L.;Nohrenberg, Michael;Leroi, Marcel M.;McMaster, Christopher;Owen, Claire E.;Hardidge, Andrew;Buchanan, Russell R. C. - 通讯作者:
Buchanan, Russell R. C.
Managing Cardiovascular and Cancer Risk Associated with JAK Inhibitors.
- DOI:
10.1007/s40264-023-01333-0 - 发表时间:
2023-11 - 期刊:
- 影响因子:4.2
- 作者:
Yang, Victor;Kragstrup, Tue W.;McMaster, Christopher;Reid, Pankti;Singh, Namrata;Haysen, Stine R.;Robinson, Philip C.;Liew, David F. L. - 通讯作者:
Liew, David F. L.
Developing a deep learning natural language processing algorithm for automated reporting of adverse drug reactions
- DOI:
10.1016/j.jbi.2022.104265 - 发表时间:
2022-12-09 - 期刊:
- 影响因子:4.5
- 作者:
McMaster, Christopher;Chan, Julia;Pires, Douglas E. V. - 通讯作者:
Pires, Douglas E. V.
McMaster, Christopher的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('McMaster, Christopher', 18)}}的其他基金
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2021
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2020
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
氧甾醇结合蛋白 Kes1 对脂质代谢和囊泡运输的调节
- 批准号:
203103-2012 - 财政年份:2016
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
氧甾醇结合蛋白 Kes1 对脂质代谢和囊泡运输的调节
- 批准号:
203103-2012 - 财政年份:2015
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
氧甾醇结合蛋白 Kes1 对脂质代谢和囊泡运输的调节
- 批准号:
203103-2012 - 财政年份:2014
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
氧甾醇结合蛋白 Kes1 对脂质代谢和囊泡运输的调节
- 批准号:
203103-2012 - 财政年份:2013
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
氧甾醇结合蛋白 Kes1 对脂质代谢和囊泡运输的调节
- 批准号:
203103-2012 - 财政年份:2012
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Cell biological role of the phosphoinositide and sterol binding protein kes1p
磷酸肌醇和甾醇结合蛋白 kes1p 的细胞生物学作用
- 批准号:
203103-2007 - 财政年份:2011
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Cell biological role of the phosphoinositide and sterol binding protein kes1p
磷酸肌醇和甾醇结合蛋白 kes1p 的细胞生物学作用
- 批准号:
203103-2007 - 财政年份:2010
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
相似海外基金
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2021
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2020
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2019
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
- 批准号:
RGPIN-2017-06491 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
The role of phospholipid scramblase 3 in the regulation of lipid synthesis by DGK-delta
磷脂扰乱酶 3 在 DGK-delta 调节脂质合成中的作用
- 批准号:
448914-2013 - 财政年份:2013
- 资助金额:
$ 2.91万 - 项目类别:
University Undergraduate Student Research Awards