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Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1

Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
主转录因子 Opi1 调节磷脂合成
批准号:
RGPIN-2017-06491
负责人:
McMaster, Christopher
金额:
$2.91万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
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英文摘要
Opi1 is an amphipathic transcriptional repressor that regulates phospholipid synthesis. Phosphatidic acid (PA) is a phospholipid biosynthetic intermediate whose level in the endoplasmic reticulum (ER) regulate Opi1 ER binding. Upon release from the ER Opi1 enters the nucleus where is acts as a transcriptional repressor of a plethora of phospholipid biosynthetic genes.
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Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
  • 批准号:
    RGPIN-2017-06491
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.83万
  • 财政年份:
    2021
  • 负责人:
    McMaster, Christopher
  • 依托单位:
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
  • 批准号:
    RGPIN-2017-06491
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2020
  • 负责人:
    McMaster, Christopher
  • 依托单位:
Regulation of Phospholipid Synthesis by the Master Transcription Factor Opi1
  • 批准号:
    RGPIN-2017-06491
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2018
  • 负责人:
    McMaster, Christopher
  • 依托单位:
Regulation of Lipid Metabolism and Vesicular Trafficking by the Oxysterol Binding Protein Kes1
  • 批准号:
    203103-2012
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2016
  • 负责人:
    McMaster, Christopher
  • 依托单位:
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