To roles of EPH kinases in regulating catecholamine secretion in chromaffin cells

点击翻译按钮获取中文摘要

The applicant is a pioneer in research on erythropoietin-producing hepatocyte kinases (EPHs). These studies represent a major, long-term program since 2000 (with funding from NSERC and other sources). The objectives of this long-term program focus on elucidating underlying mechanisms at the cellular and molecular levels with regard to how different EPHs and their ligand ephrins (EFNs) modulate blood pressure (BP) and the immune system. Three to 6 Ph.D. students will be trained in the next 10 years in this program.