Isomorphisms in tropomyosin modulate binding, flexibility and thin filament function

原肌球蛋白的同构调节结合、柔韧性和细丝功能

• 批准号: RGPIN-2017-06010
• 负责人: Heeley, David
• 金额: $ 1.89万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=629463
• 关键词: Isomorphisms; tropomyosin; modulate; binding; flexibility

Living organisms move. The most spectacular examples are muscles that have a striped appearance under the microscope. We rely on them daily for blood circulation, posture, speed & strength. These basics of life arise from the interplay of motion-producing (myofilament) proteins. One of these, tropomyosin, is the focus of the application.

活着的有机体会移动。最壮观的例子是在显微镜下有条纹外观的肌肉。我们每天都依靠它们来实现血液循环、姿势、速度和力量。这些基本的生命起源于产生运动的(肌丝)蛋白质的相互作用。其中，原肌球蛋白是应用的重点。