The regulation of adipose-derived MIF: A novel secretory function of preadipocytes mediated by PAR2

点击翻译按钮获取中文摘要

Adipose tissue is commonly considered as an organ system responsible for energy storage, temperature regulation and wound healing, yet it is also an important endocrine organ which secrets hormones and inflammatory factors that mediate metabolic process in mammals. The molecular mechanisms in regulating the secretory function of adipose tissue are largely unknown and revealing these mechanisms will have important implications for animal physiology and biochemistry. Thus, our long-term goal is to elucidate how adipose tissue orchestrates whole-body metabolism as an endocrine organ.