SIGNIFICANCE OF THE MULTIFUNCTIONAL INSULIN-LIKE GROWTH FACTOR-II RECEPTOR IN REGULATING NORMAL BRAIN FUNCTION
多功能胰岛素样生长因子 II 受体在调节正常脑功能中的意义
基本信息
- 批准号:RGPIN-2017-05729
- 负责人:
- 金额:$ 1.89万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The insulin-like growth factor-II (IGF-II) receptor is a single-pass multifunctional glycoprotein containing a large extracellular domain and a small cytoplasmic tail. The receptor interacts with IGF-II and mannose 6-phosphate (M6P)-bearing ligands, such as lysosomal enzymes
胰岛素样生长因子-II(IGF-II)受体是一种单程多功能糖蛋白,含有一个大的胞外结构域和一个小的胞浆尾巴。该受体与IGF-II和含甘露糖6-磷酸(M6P)的配体相互作用,如溶酶体酶
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kar, Satyabrata其他文献
Development of a portable hypoxia chamber for ultra-high dose rate laser-driven proton radiobiology applications.
- DOI:
10.1186/s13014-022-02024-3 - 发表时间:
2022-04-15 - 期刊:
- 影响因子:3.6
- 作者:
Chaudhary, Pankaj;Gwynne, Deborah C.;Odlozilik, Boris;McMurray, Aaron;Milluzzo, Giuliana;Maiorino, Carla;Doria, Domenico;Ahmed, Hamad;Romagnani, Lorenzo;Alejo, Aaron;Padda, Hersimerjit;Green, James;Carroll, David;Booth, Nicola;McKenna, Paul;Kar, Satyabrata;Petringa, Giada;Catalano, Roberto;Cammarata, Francesco P.;Cirrone, Giuseppe A. P.;McMahon, Stephen J.;Prise, Kevin M.;Borghesi, Marco - 通讯作者:
Borghesi, Marco
Increased Activity and Altered Subcellular Distribution of Lysosomal Enzymes Determine Neuronal Vulnerability in Niemann-Pick Type C1-Deficient Mice
- DOI:
10.2353/ajpath.2009.081096 - 发表时间:
2009-12-01 - 期刊:
- 影响因子:6
- 作者:
Amritraj, Asha;Peake, Kyle;Kar, Satyabrata - 通讯作者:
Kar, Satyabrata
Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology.
- DOI:
10.1016/j.bioactmat.2022.05.030 - 发表时间:
2022-11 - 期刊:
- 影响因子:18.9
- 作者:
Anand, Bibin;Wu, Qi;Nakhaei-Nejad, Maryam;Karthivashan, Govindarajan;Dorosh, Lyudmyla;Amidian, Sara;Dahal, Abhishek;Li, Xiuju;Stepanova, Maria;Wille, Holger;Giuliani, Fabrizio;Kar, Satyabrata - 通讯作者:
Kar, Satyabrata
Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine
- DOI:
10.1016/j.cbi.2019.03.003 - 发表时间:
2019-05-01 - 期刊:
- 影响因子:5.1
- 作者:
Baker, Glen;Matveychuk, Dmitriy;Kar, Satyabrata - 通讯作者:
Kar, Satyabrata
Role of Cathepsin D in U18666A-induced Neuronal Cell Death POTENTIAL IMPLICATION IN NIEMANN-PICK TYPE C DISEASE PATHOGENESIS
- DOI:
10.1074/jbc.m112.412460 - 发表时间:
2013-02-01 - 期刊:
- 影响因子:4.8
- 作者:
Amritraj, Asha;Wang, Yanlin;Kar, Satyabrata - 通讯作者:
Kar, Satyabrata
Kar, Satyabrata的其他文献
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{{ truncateString('Kar, Satyabrata', 18)}}的其他基金
SIGNIFICANCE OF THE MULTIFUNCTIONAL INSULIN-LIKE GROWTH FACTOR-II RECEPTOR IN REGULATING NORMAL BRAIN FUNCTION
多功能胰岛素样生长因子 II 受体在调节正常脑功能中的意义
- 批准号:
RGPIN-2017-05729 - 财政年份:2021
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
SIGNIFICANCE OF THE MULTIFUNCTIONAL INSULIN-LIKE GROWTH FACTOR-II RECEPTOR IN REGULATING NORMAL BRAIN FUNCTION
多功能胰岛素样生长因子 II 受体在调节正常脑功能中的意义
- 批准号:
RGPIN-2017-05729 - 财政年份:2020
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
SIGNIFICANCE OF THE MULTIFUNCTIONAL INSULIN-LIKE GROWTH FACTOR-II RECEPTOR IN REGULATING NORMAL BRAIN FUNCTION
多功能胰岛素样生长因子 II 受体在调节正常脑功能中的意义
- 批准号:
RGPIN-2017-05729 - 财政年份:2019
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
SIGNIFICANCE OF THE MULTIFUNCTIONAL INSULIN-LIKE GROWTH FACTOR-II RECEPTOR IN REGULATING NORMAL BRAIN FUNCTION
多功能胰岛素样生长因子 II 受体在调节正常脑功能中的意义
- 批准号:
RGPIN-2017-05729 - 财政年份:2018
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Single transmembrane domain insulin-like growth factor-II receptor and G protein: potential interaction and its significance in brain function
单跨膜结构域胰岛素样生长因子-II 受体和 G 蛋白:潜在的相互作用及其对脑功能的意义
- 批准号:
203518-2011 - 财政年份:2016
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Single transmembrane domain insulin-like growth factor-II receptor and G protein: potential interaction and its significance in brain function
单跨膜结构域胰岛素样生长因子-II 受体和 G 蛋白:潜在的相互作用及其对脑功能的意义
- 批准号:
203518-2011 - 财政年份:2014
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Single transmembrane domain insulin-like growth factor-II receptor and G protein: potential interaction and its significance in brain function
单跨膜结构域胰岛素样生长因子-II 受体和 G 蛋白:潜在的相互作用及其对脑功能的意义
- 批准号:
203518-2011 - 财政年份:2013
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Single transmembrane domain insulin-like growth factor-II receptor and G protein: potential interaction and its significance in brain function
单跨膜结构域胰岛素样生长因子-II 受体和 G 蛋白:潜在的相互作用及其对脑功能的意义
- 批准号:
203518-2011 - 财政年份:2012
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Single transmembrane domain insulin-like growth factor-II receptor and G protein: potential interaction and its significance in brain function
单跨膜结构域胰岛素样生长因子-II 受体和 G 蛋白:潜在的相互作用及其对脑功能的意义
- 批准号:
203518-2011 - 财政年份:2011
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
Role of insulin-like growth factor-II/mannose 6-phosphate (IGF-II/M6P) receptor in the regulation of brain function
胰岛素样生长因子-II/甘露糖6-磷酸(IGF-II/M6P)受体在脑功能调节中的作用
- 批准号:
203518-2006 - 财政年份:2010
- 资助金额:
$ 1.89万 - 项目类别:
Discovery Grants Program - Individual
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