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Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae

Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae
C. merolae 剪接体显着减少的剪接机制和调控
批准号:
RGPIN-2017-04783
负责人:
Rader, Stephen
金额:
$2.91万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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英文摘要
From the creation of an mRNA transcript to the degradation of the protein it encodes, there are a multitude of regulatory steps in eukaryotic gene expression. One essential step in this process is pre-mRNA splicing, in which interrupting sequences are removed from nascent transcripts. Through alternative inclusion of mRNA regions, pre-mRNA splicing dramatically broadens the range of proteins encoded by a particular gene, and provides additional regulatory layers that allow a cell to respond to environmental conditions, developmental signals, and cell cycle progression. Our understanding of this process, however, comes from a very limited range of model organisms with a strong taxonomic bias towards metazoans and fungi.
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Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae
  • 批准号:
    RGPIN-2017-04783
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2022
  • 负责人:
    Rader, Stephen
  • 依托单位:
Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae
  • 批准号:
    RGPIN-2017-04783
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2021
  • 负责人:
    Rader, Stephen
  • 依托单位:
Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae
  • 批准号:
    RGPIN-2017-04783
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2020
  • 负责人:
    Rader, Stephen
  • 依托单位:
Mechanism and regulation of splicing in the dramatically reduced spliceosome of C. merolae
  • 批准号:
    RGPIN-2017-04783
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.91万
  • 财政年份:
    2019
  • 负责人:
    Rader, Stephen
  • 依托单位:
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  • 项目类别:
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