Understanding neuromusculoskeletal interactions underlying biomechanics and control of the human hand

了解生物力学和人手控制的神经肌肉骨骼相互作用

• 批准号: RGPIN-2017-04097
• 负责人: Kociolek, Aaron
• 金额: $ 1.68万
• 依托单位: Nipissing University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630161
• 关键词: Understanding; neuromusculoskeletal; interactions; underlying; biomechanics

Dexterous hand function is a defining feature of the human identity. The hand is vitally important in nearly all activities of daily living, from getting dressed in the morning to preparing dinner in the evening. The fully opposable thumb is especially crucial to hand function, enabling interaction with objects and tools via gripping or pinching. While the hand’s versatility is a central theme in modern human ingenuity, its complex anatomy challenges our understanding of mechanical function and neuromuscular control. Successful performance of a hand-intensive task ultimately relies on the seamless interaction of neurophysiological (e.g. sensory and motor nerves) and biomechanical apparatus (e.g. muscles and tendons). However, there is an immense need to investigate how these systems interact with each other to preserve hand function, especially during complex occupational tasks that require online control of postures and grip forces. My research will use an innovative, inter-disciplinary approach to investigate hand biomechanics and neuromuscular control. This research will be organized in three themes: (1) Determining mechanical interactions; (2) Elucidating links between biomechanics and neurophysiology by experimentally manipulating sensorimotor pathways; (3) Developing a computer model capable of representing neuromusculoskeletal coupling within the hand.

灵巧的手功能是人类身份的定义特征。手在几乎所有的日常生活活动中都是至关重要的，从早上穿衣服到晚上准备晚餐。完全可对置的拇指对于手的功能尤其重要，可以通过抓握或捏握来与物体和工具进行交互。虽然手的多功能性是现代人类创造力的中心主题，但其复杂的解剖结构挑战了我们对机械功能和神经肌肉控制的理解。手部密集型任务的成功执行最终依赖于神经生理学（例如感觉和运动神经）和生物力学装置（例如肌肉和肌腱）的无缝交互。然而，有一个巨大的需要，以调查这些系统如何相互作用，以保持手的功能，特别是在复杂的职业任务，需要在线控制姿势和握力。我的研究将采用创新的跨学科方法来研究手部生物力学和神经肌肉控制。这项研究将分为三个主题：（1）确定机械相互作用;（2）通过实验操纵感觉运动通路阐明生物力学和神经生理学之间的联系;（3）开发能够代表手部神经肌肉骨骼耦合的计算机模型。