Determinants of Signal Characteristics in a Retinal Network: Contribution of Local Field Potentials and Spike Trains.

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The teamwork research taking place in my lab share the common objective of a better comprehension of how the neural activity of the various cell populations of the retina translates a visual stimulus into a neural code that can be understood by the brain. We have been using for many years the electroretinogram (ERG), a composite signal collected non-invasively at the surface of the cornea, to decipher the relative contribution of different cell population. More recently, we have gained expertise in the multi electrode array (MEA), a technology that allows the ex-vivo (isolated retina) recording of both the ERG-like signal and the spiking activity of the ganglion cells, the population giving rise to the efferent message of the retina.