Neural circuits and mechanisms of context specific conditioned inhibition

上下文特定条件抑制的神经回路和机制

• 批准号: RGPIN-2015-06347
• 负责人: McDonald, Robert
• 金额: $ 5.17万
• 依托单位: University of Lethbridge
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631399
• 关键词: Neural; circuits; mechanisms; context; specific

The abilities to learn and remember constitute two important functions mediated by the mammalian brain.  One fundamental learning and memory function that most organisms possess is the ability to discriminate between different cues and contexts.  Of particular interest is the demonstration that during discrimination learning, reinforced cues acquire excitatory and non-reinforced cues acquire inhibitory associations.

学习和记忆能力是由哺乳动物大脑调节的两个重要功能。大多数生物体拥有的一个基本学习和记忆功能是区分不同线索和背景的能力。特别有趣的是，在辨别学习过程中，强化的线索获得兴奋，而非强化的线索获得抑制联系。