Deciphering decision making: exploring the interactions between neural and neurochemical systems underlying the evaluation versus employment of cognitive effort in rats

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Most of the key decisions that determine our economic success involve the choice between something easy that provides lower returns, or something difficult that, should we succeed, provides great reward. Understanding how our brains make such decisions is one of the primary goals of the academic disciplines of cognitive and behavioural neuroscience. A lot of useful information is obtained from studying the decision making of healthy volunteers in laboratory-based games, but it is often hard to determine whether relationships observed between, say, brain activity and choice patterns indicate that a brain region is