Development of Catalysts for Asymmetric Reactions and Energy Conversion.

不对称反应和能量转换催化剂的开发。

• 批准号: RGPIN-2016-04696
• 负责人: Bergens, Steven
• 金额: $ 3.35万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632358
• 关键词: Development; Catalysts; Asymmetric; Reactions; Energy

The efficient production of pharmaceuticals and the storage/transformation of energy from renewable sources are fundamental, vital objectives of modern chemical research. Our first project builds on our discovery of an efficient amide hydrogenation catalyst. The reduction of amides in industry typically utilizes stoichiometric main-group hydrides. These flammable hydrides must be transported, and their use requires a dangerous, exothermic hydrolysis that generates waste. Catalytic amide hydrogenation eliminates these negatives, and Pharma has identified the development of such a reaction as a key need to reduce the costs and environmental impact of pharmaceutical production. We recently discovered that Ru(Ph

药物的高效生产和可再生能源的储存/转化是现代化学研究的基本、至关重要的目标。我们的第一个项目建立在我们发现了一种高效的酰胺加氢催化剂的基础上。在工业中，酰胺的还原通常使用化学计量主族氢化物。这些易燃氢化物必须运输，使用它们需要危险的、放热的水解过程，从而产生废物。催化酰胺加氢消除了这些负面影响，Pharma公司已将这种反应的开发确定为降低制药生产成本和环境影响的关键需要。我们最近发现Ru(Ph)