Vibrational spectrochemical imaging studies of materials from macro to nanoscale

关键的化学相互作用发生在纳米级，但在每个维度都有影响。我和我的学生解决了在从千分之一到十亿分之一米的长度尺度上成像材料化学过程中固有的挑战，使用模型系统进行原理证明。具体来说，我们用可见光和红外光探测物质的化学成分，使用一种称为振动光谱的技术。通过这个项目，我努力成为振动光谱化学成像领域的世界领导者，培训年轻科学家突破性技术，解决与重要材料和环境问题相关的难题。我的短期目标代表现实世界的问题，从纳米到宏观分辨率尺度，从可再生资源制成的新材料到气候变化对北极海冰硅藻的影响，海洋食物网的关键成员。我们将振动光谱学的既定原理应用于科学前沿，使用最佳衍射极限光学器件、我们新获得专利的红外断层扫描配件以及突破红外衍射极限的超分辨率技术。我们设计了新的方法来保留天然分子结构，使我们能够阐明局部化学，并准确解释这种以前无法访问的微观和纳米级数据。

Critical chemical interactions occur at the nanoscale but have impact at every dimension. My students and I tackle the challenges inherent in imaging the chemistry of materials at length scales from one thousandth to one billionth of a meter, using model systems for proof of principle. Specifically, we probe the chemical composition of matter with visible and infrared light, using a technique called vibrational spectroscopy. With this program, I strive to be a world leader in vibrational spectrochemical imaging, training young scientists in groundbreaking techniques to solve puzzles related to important materials and environmental issues. My short term objectives represent real-world problems that span the nano to macro resolution scale, in new materials made from renewable resources to the impact of climate change on Arctic sea ice diatoms, key members of the marine food web. We take established principles of vibrational spectroscopy to the scientific frontier, using best diffraction-limited optics, our newly-patented accessory for infrared tomography, and super-resolution techniques that break the infrared diffraction limit. We devise novel methods to retain native molecular architecture, allowing us to elucidate localized chemistry and make accurate interpretations of this previously inaccessible micro and nanoscale data.