Robust Correction for the Effects of Head Motion on Functional Magnetic Resonance Imaging of Brain Activity

头部运动对大脑活动功能磁共振成像影响的鲁棒校正

• 批准号: RGPIN-2017-06040
• 负责人: Graham, Simon
• 金额: $ 4.08万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632931
• 关键词: Robust; Correction; Effects; Head; Motion

Although functional magnetic resonance imaging (fMRI) is widely used as a neuroscience research tool to measure and understand brain activity, sensitivity to head motion poses a major problem. Even millimetre head motions can disrupt fMRI maps of brain activity in complex ways. Young adults can usually remain sufficiently still, but other populations such as children, the elderly, and people with impaired brain function often find it very difficult. In such cases, the fMRI data are often discarded. The head motion problem is thus a barrier to expanding use of fMRI in basic and clinical neuroscience research.

虽然功能性磁共振成像（fMRI）被广泛用作神经科学研究工具来测量和了解大脑活动，但对头部运动的敏感性构成了一个主要问题。即使是毫米级的头部运动也会以复杂的方式扰乱大脑活动的功能磁共振成像图。年轻人通常可以保持足够的静止，但其他人群，如儿童，老年人和大脑功能受损的人往往发现这很困难。在这种情况下，fMRI数据往往被丢弃。因此，头部运动的问题是一个障碍，扩大使用功能磁共振成像在基础和临床神经科学研究。