权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Expanding the use of high-speed sCMOS cameras into selective 3-dimensional imaging

将高速 sCMOS 相机的使用扩展到选择性 3 维成像

基本信息

批准号：
515504-2017
负责人：
Yethiraj, Anand
金额：
$ 1.82万
依托单位：
Memorial University of Newfoundland
依托单位国家：
加拿大
项目类别：
Engage Grants Program
财政年份：
2017
资助国家：
加拿大
起止时间：
2017-01-01 至 2018-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=639282
关键词：
Expanding use speed sCMOS cameras

项目摘要

High-speed cameras have provided unprecedented ability to look at biological live-cell processes in real time aswell as machine vision in manufacturing processes. In both cases, one obtains two-dimensional image series ofthree-dimensional objects. Accessing real-time information outside a two-dimensional (X-Y) plane, i.e., in X,Y, and Z dimensions, is a challenge. Typical confocal scanning microscopes address the problem ofvisualization in 3 dimensions. However, such microscopes are expensive (of order $500,000) and, nevertheless,have limited capabilities for processes that involve high-speed out-of-plane motions.Accessing real-time information in three dimensions has been a challenge that our commercial partner, OptikonCorporation Ltd., is keen to resolve. To solve this problem, the proposed collaborative work aims to establish aprocedure that uses known components - a scientific CMOS camera (sCMOS), along with high speed focusingoptics - to get 3D information without requiring true confocal scanning. The end point of this proposal wouldbe a Technical Application Note that enables future purchasers of sCMOS cameras from the commercialpartner, Optikon Corporation Ltd., to have access to clear guidelines on how to integrate high-speed focusingoptics with a sCMOS camera in order to be able to visualize multiple regions in X,Y and Z in real time.

高速摄像机提供了前所未有的能力来观察生物活细胞过程中的真实的时间以及机器视觉在制造过程中。在这两种情况下，人们获得三维物体的二维图像系列。- 在二维（X-Y）平面之外，即，在X、Y和Z维度上，这是一个挑战。典型的共焦扫描显微镜解决了三维可视化的问题。然而，这样的显微镜是昂贵的（大约500，000美元），并且尽管如此，对于涉及高速平面外运动的过程具有有限的能力。三维中的实时信息一直是我们的商业合作伙伴OptikonCorporation Ltd.渴望解决。为了解决这个问题，拟议的合作工作旨在建立一个程序，使用已知的组件-科学CMOS相机（sCMOS），沿着高速聚焦光学-获得3D信息，而不需要真正的共焦扫描。该提案的最终目的是一份技术应用说明，使未来的sCMOS相机购买者能够从商业合作伙伴Optikon Corporation Ltd.，获得关于如何将高速聚焦光学器件与sCMOS相机集成的明确指导，以便能够真实的实时显示X、Y和Z方向的多个区域。