Extraction optimization of the bioactive content from a series of New Brunswick's wildlife natural products

新不伦瑞克省一系列野生动物天然产品中生物活性成分的提取优化

• 批准号: 514819-2017
• 负责人: Boudreau, Luc
• 金额: $ 1.82万
• 依托单位: Université de Moncton
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=639326
• 关键词: Extraction; optimization; bioactive; content; series

The inflammatory response is a necessary process of the human body towards the defense against exteriorpathogens. While the inflammatory response is mostly beneficial for the human body, unregulated andpersistent inflammation can lead to tissue damage. Spruce pitch is a natural product abundantly found in NewBrunswick's flora that exert multiple beneficial properties to the human body. Mr Peter Porter, president ofSavonnerie Olivier from St-Anne de Kent, New Brunswick, approached the research team to investigate theeffects of spruce pitch on the inflammatory response of the immune system. Savonnerie Olivier has severalnatural products on the market derived from numerous wildlife products. While continuing the development ofnovel and innovative natural product, the company is interested in pursuing local spruce pitch as a potentialnew product. Unfortunately, the optimal extraction process for the bioactive content spruce pitch remainslargely unknown. For this collaboration, our primary objective will be to determine the best approach to extractthe bioactive content from spruce pitch. To achieve our objective, Spruce pitch will be collected in variouslocations in New Brunswick and subsequently sent to my laboratory for initial bioactive content extraction. Inconclusion, my laboratory will contribute to the elucidation of the optimal extraction process of the bioactivecontent found in spruce pitch salve. As a natural product company, Savonnerie Olivier will benefit from thisresearch by having a scientific backing for their product, a rare opportunity among natural products companies.

炎症反应是人体防御外界病原体的必要过程。虽然炎症反应大多对人体有益，但不受控制和持续的炎症会导致组织损伤。云杉沥青是一种天然产品，在新不伦瑞克省的植物群中大量发现，对人体有多种有益的特性。来自新不伦瑞克圣安妮肯特的savonnerie Olivier的总裁彼得·波特先生找到了研究小组，调查云杉沥青对免疫系统炎症反应的影响。Savonnerie Olivier在市场上有几种从众多野生动物产品中提取的天然产品。在继续开发新颖和创新的天然产品的同时，公司有兴趣将当地云杉沥青作为潜在的新产品。不幸的是，提取云杉沥青生物活性成分的最佳工艺仍然是未知的。对于这次合作，我们的主要目标将是确定从云杉沥青中提取生物活性成分的最佳方法。为了实现我们的目标，云杉沥青将在新不伦瑞克省的不同地点收集，然后送到我的实验室进行初步的生物活性成分提取。总之，我的实验室将有助于阐明云杉沥青药膏中生物活性成分的最佳提取工艺。作为一家天然产品公司，Savonnerie Olivier将从这项研究中受益，因为他们的产品有科学支持，这在天然产品公司中是一个难得的机会。