Environmental micro-biosensor for detection of polycyclic aromatic hydrocarbons in soil

用于检测土壤中多环芳烃的环境微生物传感器

• 批准号: 508767-2017
• 负责人: Whalen, Joann
• 金额: $ 1.82万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=639681
• 关键词: Environmental; micro; biosensor; detection; polycyclic

Polycyclic aromatic hydrocarbons (PAHs) include several hundred chemically-related, environmentallypersistent organic compounds having various structures and varied toxicity. Most of them are formed by aprocess of thermal decomposition (pyrolysis) and subsequent recombination (pyrosynthesis) of organicmolecules from industries such as petroleum and coal PAHs are ubiquitous in Canadian soils and of concernfor human and ecosystem health due to their toxicity as carcinogens, mutagens and immunosuppressants. Theindustrial partner, Qanari Inc., has developed and validated the Safe Soil Tester, a rapid diagnostic tool thatuses a bioluminescent microorganism to qualitatively detect the presence of PAHs in contaminated soils. Whencoupled with global positioning systems, the diagnosis produces maps indicating 'hotspots' of contaminationfor further evaluation, risk assessment and remediation. Current market demands for hand-held technologieshave led Qanari to investigate the possibility of developing a micro-biosensor system that would be a smaller,portable device that is compatible with wireless technology. Qanari and McGill University will collaborate todemonstrate the proof-of-concept of a micro-biosensor and detection system, to determine the feasibility ofmicro-sizing the existing technology. Given the increasingly stringent regulations dealing with contaminationfrom PAHs in upstream oil and gas sites, petroleum storage tank sites, as well as other commercial andindustrial facilities, such a rapid detection system has tremendous commercial potential. The Canadian publicwill benefit from quick screening tools to mitigate the effect of PAHs on human and ecosystem health.

多环芳烃（PAHs）包括数百种结构各异、毒性各异的化学相关的环境持久性有机化合物。其中大多数是由来自石油和煤炭等工业的有机分子的热分解（热解）和随后的重组（热解合成）过程形成的。工业合作伙伴Qanari Inc.开发并验证了安全土壤测试仪，这是一种快速诊断工具，使用生物发光微生物定性检测污染土壤中多环芳烃的存在。当与全球定位系统相结合时，诊断产生了指示污染“热点”的地图，以供进一步评估、风险评估和补救。目前市场对手持技术的需求促使Qanari研究开发微型生物传感器系统的可能性，该系统将是一种与无线技术兼容的小型便携式设备。卡纳里和麦吉尔大学将合作演示微型生物传感器和检测系统的概念验证，以确定现有技术微型化的可行性。鉴于对上游石油和天然气站点、石油储罐站点以及其他商业和工业设施中的多环芳烃污染的日益严格的法规，这种快速检测系统具有巨大的商业潜力。加拿大公众将受益于快速筛选工具，以减轻多环芳烃对人类和生态系统健康的影响。