Color Encoded Speckle Imaging for Micro-Ultrasound

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Micro-resolution ultrasound imaging has emerged in the past two decades as a new non-invasive tool forassessing structural and functional details of living tissues in fine scale. It is nowadays possible to use thisimaging tool to map cardiovascular dynamics through an operating mode known as color flow imaging (basedon Doppler ultrasound principles). However, this mode can provide limited insights on blood flow dynamicsinside the circulation. There is a need for engineering innovations that can enhance the quality of blood flowvisualization in micro-ultrasound.In this project, initial efforts will be dedicated to develop color encoded speckle imaging (CESI) as a newcardiovascular imaging mode for micro-ultrasound. CESI is a new flow visualization algorithm that offersduplex rendering of flow trajectory (highlighted by flow speckle motion) and flow speed (depicted throughDoppler-based velocity color coding). Over the project period, proof-of-concept implementation of CESI formicro-ultrasound will be pursued, and flow phantom experiments will be conducted to test its performance. Itis anticipated that the feasibility of realizing CESI as a new micro-ultrasound flow imaging mode will beestablished by the end of this project. Such technical endeavor will economically benefit Canada bystrengthening the country's position as a global leader in micro-ultrasound imaging.