Improved powder production processes
改进粉末生产工艺
基本信息
- 批准号:518095-2017
- 负责人:
- 金额:$ 0.91万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Engage Plus Grants Program
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This project will continue work aimed at understanding how process parameters affect an existing technology developed by us for freeze-drying biological and medical solutions to produce powders. Freeze-dried bio-medical powders are used in pharmaceuticals as well as for food. The technology we will employ in this project is called atmospheric spray freeze drying (ASFD) and has the potential to be faster and more economical than current methods and to work for a wider variety of substances than allowed for by current methods. During our previous Engage grant, we improved the monitoring and process control of our AFSD equipment. In the proposed work, we will examine the effects of different process parameter variations on the attributes of the powders produced with AFSD. This work will aim towards optimization of process parameters to produce powders with given desired properties. Use of AFSD will be explored using pharmaceutical formulations of interest to the industry partner and comparison to conventional tray freeze-drying will be made. As part of the proposed research, we will examine the ability of AFSD to produce dried material with desired properties but with reduced processing time and cost compared to the other methods used by the industry partner. In addition, we wish to continue improving our understanding of how process parameters and their control affect the essential properties of atmospheric spray freeze dried material.
该项目将继续致力于了解工艺参数如何影响我们开发的现有技术,用于冷冻干燥生物和医疗解决方案以生产粉末。冷冻干燥的生物医学粉末用于药品和食品。我们将在该项目中采用的技术称为常压喷雾冷冻干燥(ASFD),具有比现有方法更快,更经济的潜力,并且适用于比现有方法更广泛的物质。在我们上一次的Engage赠款中,我们改进了AFSD设备的监测和过程控制。在拟议的工作中,我们将研究不同的工艺参数变化对AFSD生产的粉末属性的影响。这项工作的目的是优化工艺参数,以生产具有所需性能的粉末。将使用行业合作伙伴感兴趣的药物配方探索AFSD的使用,并与传统的托盘冷冻干燥进行比较。作为拟议研究的一部分,我们将研究AFSD生产具有所需特性的干燥材料的能力,但与行业合作伙伴使用的其他方法相比,加工时间和成本更低。此外,我们希望继续提高我们对工艺参数及其控制如何影响常压喷雾冷冻干燥材料基本特性的理解。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Finlay, Warren其他文献
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{{ truncateString('Finlay, Warren', 18)}}的其他基金
Development of Idealized Geometries that Mimic Upper Airway Deposition of Aerosols and Sprays
开发模拟气溶胶和喷雾剂上呼吸道沉积的理想几何形状
- 批准号:
RGPIN-2017-04036 - 财政年份:2021
- 资助金额:
$ 0.91万 - 项目类别:
Discovery Grants Program - Individual
Development of Idealized Geometries that Mimic Upper Airway Deposition of Aerosols and Sprays
开发模拟气溶胶和喷雾剂上呼吸道沉积的理想几何形状
- 批准号:
RGPIN-2017-04036 - 财政年份:2020
- 资助金额:
$ 0.91万 - 项目类别:
Discovery Grants Program - Individual
Development of Idealized Geometries that Mimic Upper Airway Deposition of Aerosols and Sprays
开发模拟气溶胶和喷雾剂上呼吸道沉积的理想几何形状
- 批准号:
RGPIN-2017-04036 - 财政年份:2019
- 资助金额:
$ 0.91万 - 项目类别:
Discovery Grants Program - Individual
Development of Idealized Geometries that Mimic Upper Airway Deposition of Aerosols and Sprays
开发模拟气溶胶和喷雾剂上呼吸道沉积的理想几何形状
- 批准号:
RGPIN-2017-04036 - 财政年份:2018
- 资助金额:
$ 0.91万 - 项目类别:
Discovery Grants Program - Individual
Development of Idealized Geometries that Mimic Upper Airway Deposition of Aerosols and Sprays
开发模拟气溶胶和喷雾剂上呼吸道沉积的理想几何形状
- 批准号:
RGPIN-2017-04036 - 财政年份:2017
- 资助金额:
$ 0.91万 - 项目类别:
Discovery Grants Program - Individual
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