Scanning histology and immunohistochemistry-prepared tissue for bridging across scales of molecular, cellular, systems and imaging neuroscience
Scanning histology and immunohistochemistry-prepared tissue for bridging across scales of molecular, cellular, systems and imaging neuroscience
批准号:
RTI-2018-00953
负责人:
Shmuel, Amir
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
我们需要一个尖端的系统,用于高通量、高分辨率的脑组织光学扫描。在扫描之前,从实验动物的大脑中提取组织,切成切片,装在载玻片上,并根据各种组织学,免疫荧光或免疫组织化学协议进行处理。我们还将使用扫描仪验证光遗传构建体的选择性表达,并验证转基因/Cre动物系中的荧光表达。
英文摘要
We request a cutting edge system for high throughput, high resolution optical scanning of brain tissue. Prior to the scanning, the tissue is extracted from brains of experimental animals, sectioned into slices that are mounted on slides, and processed according to various histology, immunofluorescence or immunohistochemistry protocols. We will also use the scanner to validate the selective expression of optogenetic constructs and to validate fluorescence expression in transgenic/Cre animal lines.
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会议论文
Unraveling the mesoscopic functional organization of the human visual cortex using high-field MRI
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批准号:RGPIN-2020-06930
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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财政年份:2022
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负责人:Shmuel, Amir
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依托单位:
A cutting-edge radio-frequency coil for structural and functional MRI of the primate brain at ultra-high magnetic field
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批准号:RTI-2023-00553
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项目类别:Research Tools and Instruments
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资助金额:$10.84万
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财政年份:2022
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负责人:Shmuel, Amir
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依托单位:
Unraveling the mesoscopic functional organization of the human visual cortex using high-field MRI
-
批准号:RGPIN-2020-06930
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.42万
-
财政年份:2021
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负责人:Shmuel, Amir
-
依托单位:
Unraveling the mesoscopic functional organization of the human visual cortex using high-field MRI
-
批准号:RGPIN-2020-06930
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.42万
-
财政年份:2020
-
负责人:Shmuel, Amir
-
依托单位:
Mechanisms of high-resolution functional imaging and of decoding information conveyed by cortical columns
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批准号:RGPIN-2015-05103
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2019
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负责人:Shmuel, Amir
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依托单位:
Mechanisms of high-resolution functional imaging and of decoding information conveyed by cortical columns
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批准号:RGPIN-2015-05103
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项目类别:Discovery Grants Program - Individual
-
资助金额:$4.15万
-
财政年份:2018
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负责人:Shmuel, Amir
-
依托单位:
Mechanisms of high-resolution functional imaging and of decoding information conveyed by cortical columns
-
批准号:RGPIN-2015-05103
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$4.15万
-
财政年份:2017
-
负责人:Shmuel, Amir
-
依托单位:
Mechanisms of high-resolution functional imaging and of decoding information conveyed by cortical columns
-
批准号:RGPIN-2015-05103
-
项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2016
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负责人:Shmuel, Amir
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依托单位:
Mechanisms of high-resolution functional imaging and of decoding information conveyed by cortical columns
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批准号:RGPIN-2015-05103
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2015
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负责人:Shmuel, Amir
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依托单位:
Neurophysiological mechanisms of visual perception: interactions between lower visual areas
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批准号:375457-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2014
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负责人:Shmuel, Amir
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依托单位:
Neurophysiological mechanisms of visual perception: interactions between lower visual areas
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批准号:375457-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2012
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负责人:Shmuel, Amir
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依托单位:
Modeling and validating the effect of transcranial magnetic stimulation on cortical excitability: implications for post-stroke recovery and depression
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批准号:385962-2010
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项目类别:Collaborative Health Research Projects
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资助金额:$5.04万
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财政年份:2012
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负责人:Shmuel, Amir
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依托单位:
Modeling and validating the effect of transcranial magnetic stimulation on cortical excitability: implications for post-stroke recovery and depression
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批准号:385962-2010
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项目类别:Collaborative Health Research Projects
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资助金额:$6.43万
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财政年份:2011
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负责人:Shmuel, Amir
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依托单位:
Neurophysiological mechanisms of visual perception: interactions between lower visual areas
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批准号:375457-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2011
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负责人:Shmuel, Amir
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依托单位:
Modeling and validating the effect of transcranial magnetic stimulation on cortical excitability: implications for post-stroke recovery and depression
-
批准号:385962-2010
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项目类别:Collaborative Health Research Projects
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资助金额:$4.91万
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财政年份:2010
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负责人:Shmuel, Amir
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依托单位:
Neurophysiological mechanisms of visual perception: interactions between lower visual areas
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批准号:375457-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2010
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负责人:Shmuel, Amir
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依托单位:
Spatio-temporal simultaneous measurements of neurophysiological and hemodynamics signals using dual methods of optical imaging
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批准号:390801-2010
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$4.89万
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财政年份:2009
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负责人:Shmuel, Amir
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依托单位:
An neuronavigation system for structural and functional MRI-guided transcranial magnetic stimulation and neurophysiological recordings in non-human primates
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批准号:391158-2010
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$4.25万
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财政年份:2009
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负责人:Shmuel, Amir
-
依托单位:
Neurophysiological mechanisms of visual perception: interactions between lower visual areas
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批准号:375457-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
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财政年份:2009
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负责人:Shmuel, Amir
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依托单位:
海外基金